Recent developments in ruthenium anticancer drugs
Interest in Ru anticancer drugs has been growing rapidly since NAMI-A ((ImH+)[RuIIICl4
(Im)(S-dmso)], where Im= imidazole and S-dmso= S-bound dimethylsulfoxide) or KP1019 …
(Im)(S-dmso)], where Im= imidazole and S-dmso= S-bound dimethylsulfoxide) or KP1019 …
In situ imaging of metals in cells and tissues
R McRae, P Bagchi, S Sumalekshmy… - Chemical …, 2009 - ACS Publications
Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …
Speciation of metal drugs, supplements and toxins in media and bodily fluids controls in vitro activities
Studies of metal uptake, metabolism and excretion by single bacterial, yeast, plant and
animal cells is a widespread area of research, yet little is known about the reactivity and …
animal cells is a widespread area of research, yet little is known about the reactivity and …
Orthopaedic metals and their potential toxicity in the arthroplasty patient: a review of current knowledge and future strategies
GM Keegan, ID Learmonth… - The Journal of Bone & …, 2007 - boneandjoint.org.uk
The long-term effects of metal-on-metal arthroplasty are currently under scrutiny because of
the potential biological effects of metal wear debris. This review summarises data describing …
the potential biological effects of metal wear debris. This review summarises data describing …
Biological applications of X-ray fluorescence microscopy: exploring the subcellular topography and speciation of transition metals
CJ Fahrni - Current opinion in chemical biology, 2007 - Elsevier
Synchrotron X-ray fluorescence microscopy (SXRF) is a microanalytical technique for the
quantitative mapping of elemental distributions. Among currently available imaging …
quantitative mapping of elemental distributions. Among currently available imaging …
A systematic comparison of the actual, potential, and theoretical health effects of cobalt and chromium exposures from industry and surgical implants
GM Keegan, ID Learmonth, C Case - Critical reviews in toxicology, 2008 - Taylor & Francis
Humans are exposed to cobalt (Co) and chromium (Cr) from industry and surgical devices,
most notably orthopedic joint replacements. This review compares the potential health …
most notably orthopedic joint replacements. This review compares the potential health …
X‐ray fluorescence microprobe imaging in biology and medicine
T Paunesku, S Vogt, J Maser, B Lai… - Journal of cellular …, 2006 - Wiley Online Library
Characteristic X‐ray fluorescence is a technique that can be used to establish elemental
concentrations for a large number of different chemical elements simultaneously in different …
concentrations for a large number of different chemical elements simultaneously in different …
Imaging and speciation of trace elements in biological environment
Mineral elements, often at the trace level, play a considerable role in physiology and
pathology of biological systems. Metallogenomics, metalloproteomics, and metallomics are …
pathology of biological systems. Metallogenomics, metalloproteomics, and metallomics are …
Chemical properties and toxicity of chromium (III) nutritional supplements
The status of Cr (III) as an essential micronutrient for humans is currently under question. No
functional Cr (III)-containing biomolecules have been definitively described as yet, and …
functional Cr (III)-containing biomolecules have been definitively described as yet, and …
X-ray-induced photo-chemistry and X-ray absorption spectroscopy of biological samples
As synchrotron light sources and optics deliver greater photon flux on samples, X-ray-
induced photo-chemistry is increasingly encountered in X-ray absorption spectroscopy …
induced photo-chemistry is increasingly encountered in X-ray absorption spectroscopy …