Reactive oxygen species-responsive drug delivery systems for the treatment of neurodegenerative diseases

WC Ballance, EC Qin, HJ Chung, MU Gillette, H Kong - Biomaterials, 2019 - Elsevier
Neurodegenerative diseases and disorders seriously impact memory and cognition and can
become life-threatening. Current medical techniques attempt to combat these detrimental …

A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy

Q Liang, J Xi, XJ Gao, R Zhang, Y Yang, X Gao, X Yan… - Nano Today, 2020 - Elsevier
Enzyme-mediated activation of prodrug in tumor cells is an attractive strategy for targeted
cancer therapy. Of note, natural peroxidase and indole-3-acetic acid (IAA) have been shown …

Regulation of catechins in uric acid metabolism disorder related human diseases

D Wu, W Zhang, X Lai, Q Li, L Sun… - Mini Reviews in …, 2020 - ingentaconnect.com
Uric acid is the end product of purine metabolism in humans. High uric acid levels form
sodium urate crystals that trigger biological processes, which lead to the development of …

[HTML][HTML] Microplastics affect interspecific interactions between cladoceran species in the absence and presence of predators by triggering asymmetric individual …

J Yin, C Duan, F Zhou, L Gong, MDKL Gunathilaka… - Water Research, 2024 - Elsevier
Although many studies have reported the negative effects of microplastics on aquatic
organisms, most research is focused on individual scales. Individual studies highlight harm …

Extending the bioavailability of hydrophilic antioxidants for metal ion detoxification via crystallization with polysaccharide dopamine

R Miller, Y Kim, CG Park, C Torres, B Kim… - … Applied Materials & …, 2022 - ACS Publications
Although metal ions, such as silver and gold, have been shown to have strong antimicrobial
properties, their potential to have toxic effects on human and environmental health has …

Ecological impact of surfactant Tween-80 on plankton: High-scale analyses reveal deeper hazards

D Yuan, Y Long, D Liu, F Zhou, L Chen… - Science of The Total …, 2024 - Elsevier
The ecological risks of surfactants have been largely neglected because of their low toxicity.
Multiscale studies have indicated that even if a pollutant causes no acute toxicity in a test …

Polymeric antioxidant materials for treatment of inflammatory disorders

J Yeo, J Lee, S Lee, WJ Kim - Advanced Therapeutics, 2021 - Wiley Online Library
Reactive oxygen and nitrogen species (RONS) play a key role in physiological conditions as
signaling molecules for regulating homeostasis in the human body. However, abnormally …

In‐Drop Thermal Cycling of Microcrystal Assembly for Senescence Control with Minimal Variation in Efficacy

RC Miller, J Lee, YJ Kim, HS Han… - Advanced Functional …, 2023 - Wiley Online Library
The secretome from mesenchymal stem cells (MSCs) have recently gained attention for new
therapeutics. However, clinical application requires in vitro cell manufacturing to attain …

[HTML][HTML] Real-time heart rate monitoring system for cardiotoxicity assessment of Daphnia magna using high-speed digital holographic microscopy

IH Kwon, IY Kim, MB Heo, JW Park, SW Lee… - Science of the Total …, 2021 - Elsevier
Abstract Machine vision techniques for monitoring heart rates in aquatic bioassays have
been applied to cardiotoxicity assessment. However, the requisite large data sizes and long …

Process kinetics and regulation in reactive crystallization: Polymorphic control and morphology optimization for enhancing powder properties of thiothiamine

R Han, Y Li, S Jia, T Tao, Y Wang, L Zhou, X Li, C Zhu… - Powder Technology, 2024 - Elsevier
The important intermediate thiothiamine for Vitamin B1 production is often challenged by
issues related to mixed polymorphs and needle-shaped crystal morphology in industrial …