Background Neuropsychiatric symptoms (NPS) of dementia, such as anxiety, depression,
agitation, and apathy, are complex, stressful, and costly aspects of care, and are associated …

Background We performed an updated meta-analysis of randomized placebo-controlled
trials testing memantine monotherapy for patients with Alzheimer's disease (AD). Methods …

Background: The clinical benefit of memantine for Alzheimer's disease (AD) remains
inconclusive. Objective: We performed an updated systematic review and meta-analysis of …

Apathy is a reduction in goal-directed activity in the cognitive, behavioral, emotional, or
social domains of a patient's life and occurs in one out of three patients after stroke. Despite …

Introduction Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …

Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent and
represent a significant burden for patients and their caregivers. Early recognition and …

Background Despite the high prevalence of apathy in Alzheimer's disease (AD), and its
harmful effects, there are currently no therapies proven to treat this symptom. Recently, a …

Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) affect up to 97% of AD
patients, with an estimated 80% of current AD patients experiencing these symptoms …

Objective: Neuropsychiatric symptoms (NPS) may be the first manifestation of an underlying
neurocognitive disorder. We undertook a review to provide an update on the epidemiology …

Apathy is one of the most challenging and prevalent behavioral symptoms of dementia. It is
associated with increased disability and caregiver frustration as well as reduced quality of …