Target antigens determine graft-versus-host disease phenotype
Chronic graft-vs-host disease (cGVHD) is an increasingly frequent complication of
allogeneic stem cell transplantation. Phenotypically, cGVHD differs from patient to patient; in …
allogeneic stem cell transplantation. Phenotypically, cGVHD differs from patient to patient; in …
HLA Typing for Bone Marrow Transplantation: New Polymerase Chain Reaction—Based Methods
AB Begovich, HA Erlich - Jama, 1995 - jamanetwork.com
BONE MARROW transplantation, first introduced into clinical practice in the 1960s, has now
become an accepted form of therapy for a variety of hematologic malignancies as well as a …
become an accepted form of therapy for a variety of hematologic malignancies as well as a …
Uneven tissue distribution of minor histocompatibility proteins versus peptides is caused by MHC expression
P Griem, HJ Wallny, K Falk, O Rötzschke, B Arnold… - Cell, 1991 - cell.com
Naturally processed minor hlstocompatlblllty(H) peptides corresponding to HJb, Hy, and an
unmapped BALB. B minor H gene were quantified In a relative way in 15 different tissues of …
unmapped BALB. B minor H gene were quantified In a relative way in 15 different tissues of …
Biochemical and immunogenetic analysis of an immunodominant peptide (B6dom1) encoded by the classical H7 minor histocompatibility locus
PA Eden, GJ Christianson, P Fontaine… - The Journal of …, 1999 - journals.aai.org
Of the many minor histocompatibility (H) Ags that have been detected in mice, the ability to
induce graft vs host disease (GVHD) after bone marrow transplantation is restricted to a …
induce graft vs host disease (GVHD) after bone marrow transplantation is restricted to a …
Human minor histocompatibility antigens
M de Bueger, E Goulmy - Transplant Immunology, 1993 - Elsevier
For over five decades minor histocompatibility (mH) antigens have continued to fascinate
immunologists, mainly because of their minor but distinct role in transplantation but no less …
immunologists, mainly because of their minor but distinct role in transplantation but no less …
Evaluation of in vitro cytotoxic T lymphocyte assays as a predictive test for the occureence of graft vs host disease
P Fontaine, J Langlais, C Perreault - Immunogenetics, 1991 - Springer
The potential value of in vitro cytotoxic T lymphocyte (CTL) assays for predicting the
occurrence of graft vs host disease (GVHD) following allogeneic bone marrow …
occurrence of graft vs host disease (GVHD) following allogeneic bone marrow …
Multiple minor histocompatibility antigen disparities between a recipient and four HLA-identical potential sibling donors for bone marrow transplantation
EAF Marijt, WFJ Veenhof, E Goulmy, PMC Kluck… - Human immunology, 1993 - Elsevier
A patient with acute leukemia and her family including four HLA-identical siblings were
analyzed to select a donor who was not only HLA-but also minor histocompatility (mH) …
analyzed to select a donor who was not only HLA-but also minor histocompatility (mH) …
Self tolerance of natural MHC class I ligands
HG Rammensee, O Rötzschke… - International reviews of …, 1993 - Taylor & Francis
The central problem of the immune system is selfhonself discrimination. This is achieved by
clonal selection, essentially as postulated in the 1950s, that is, self reactive lymphocytes are …
clonal selection, essentially as postulated in the 1950s, that is, self reactive lymphocytes are …
T LYMPHOCYTE RESPONSES TO MULTIPLE MINOR HISTOCOMPATIBILITY ANTIGENS GENERATE BOTH SELF-MAJOR HISTOCOMPATIBILITY COMPLEX …
N Tremblay, P Fontaine, C Perreault - Transplantation, 1994 - journals.lww.com
Minor histocompatibility antigens (MiHA) may represent ideal targets for cancer
immunotherapy since (1) the expression of many MiHA is tissue specific and (2) they can …
immunotherapy since (1) the expression of many MiHA is tissue specific and (2) they can …
The role of MHC-associated self-peptides in transplantation and immunosurveillance
C Perreault, S Brochu, P Fontaine, N Tremblay… - Clinical immunology and …, 1994 - Elsevier
The antigen-binding site of most major histocompatibility complex (MHC) class I and II
antigens is occupied by self-peptides that are derived from the proteolysis of endogenous …
antigens is occupied by self-peptides that are derived from the proteolysis of endogenous …