Revisiting the functional anatomy of the human brain: toward a meta-networking theory of cerebral functions

G Herbet, H Duffau - Physiological Reviews, 2020 - journals.physiology.org
For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …

Mapping human brain lesions and their functional consequences

HO Karnath, C Sperber, C Rorden - Neuroimage, 2018 - Elsevier
Neuroscience has a long history of inferring brain function by examining the relationship
between brain injury and subsequent behavioral impairments. The primary advantage of this …

Mapping correlated neurological deficits after stroke to distributed brain networks

JS Siegel, GL Shulman, M Corbetta - Brain Structure and Function, 2022 - Springer
Understanding the relationships between brain organization and behavior is a central goal
of neuroscience. Traditional teaching emphasizes that the human cerebrum includes many …

An empirical comparison of univariate versus multivariate methods for the analysis of brain–behavior mapping

MV Ivanova, TJ Herron, NF Dronkers… - Human Brain …, 2021 - Wiley Online Library
Lesion symptom mapping (LSM) tools are used on brain injury data to identify the neural
structures critical for a given behavior or symptom. Univariate lesion symptom mapping …

[HTML][HTML] Relative contributions of lesion location and lesion size to predictions of varied language deficits in post-stroke aphasia

M Thye, D Mirman - NeuroImage: Clinical, 2018 - Elsevier
Despite the widespread use of lesion-symptom mapping (LSM) techniques to study
associations between location of brain damage and language deficits, the prediction of …

An empirical evaluation of multivariate lesion behaviour mapping using support vector regression

C Sperber, D Wiesen, HO Karnath - 2019 - Wiley Online Library
Multivariate lesion behaviour mapping based on machine learning algorithms has recently
been suggested to complement the methods of anatomo‐behavioural approaches in …

Rethinking causality and data complexity in brain lesion-behaviour inference and its implications for lesion-behaviour modelling

C Sperber - Cortex, 2020 - Elsevier
Modelling behavioural deficits based on structural lesion imaging is a popular approach to
map functions in the human brain, and efforts to translationally apply lesion-behaviour …

[HTML][HTML] Fluency and rule breaking behaviour in the frontal cortex

L Cipolotti, P Molenberghs, J Dominguez, N Smith… - Neuropsychologia, 2020 - Elsevier
Abstract Design (DF) and phonemic fluency tests (FAS; D-KEFS, 2001) are commonly used
to investigate voluntary generation. Despite this, several important issues remain poorly …

[HTML][HTML] Reclassifying stroke lesion anatomy

AK Bonkhoff, T Xu, A Nelson, R Gray, A Jha, J Cardoso… - Cortex, 2021 - Elsevier
Cognitive and behavioural outcomes in stroke reflect the interaction between two complex
anatomically-distributed patterns: the functional organization of the brain and the structural …

Mapping the deficit dimension structure of the National Institutes of Health Stroke Scale

B Cheng, J Chen, A Königsberg, C Mayer… - …, 2023 - thelancet.com
Summary Background The National Institutes of Health Stroke Scale (NIHSS) is the most
frequently applied clinical rating scale for standardized assessment of neurological deficits …