Pharmacophore-guided in-silico discovery of SIRT1 inhibitors for targeted cancer therapy

D Sharma, R Muniyan - Computational Biology and Chemistry, 2024 - Elsevier
Abstract Epigenetic modifier, Sirtuin (SIRTs) is a family of seven isoforms (SIRT1‐7) and
nicotinamide adenine dinucleotide (NAD+) dependent class III histone deacetylase …

[HTML][HTML] Computational evaluation of marine demospongiae sponges metabolites activity as mycolic acid biosynthesis inhibitors in Mycobacterium tuberculosis

AR Alanzi - The International Journal of Mycobacteriology, 2023 - journals.lww.com
Background: Mycobacterium tuberculosis is a bacterium that has historically had a
substantial impact on human health. Despite advances in understanding and management …

[PDF][PDF] Immunological and Molecular Analysis of Virulence and Resistance of Pseudomonas aeruginosa in Urinary Tract Infections

ZHJ Alkufaishi, LA Abdul-Lateef, AKH AL-saffar, JA Ali - publishing.emanresearch.org
Background: Pseudomonas aeruginosa is an opportunistic pathogen notorious for its role in
antibiotic resistance and nosocomial infections. This study investigates immunological …