Water freezing remains a perennial topic of great relevance to many important aspects of our
lives; from the climate to human society and from economics to medicine, frozen water …

Despite their importance in tissue homeostasis and renewal, human pituitary stem cells
(PSCs) are incompletely characterized. We describe a human single nucleus RNA-seq and …

Context: Pheochromocytomas and paragangliomas have a highly diverse genetic
background, with a third of the cases carrying a germline mutation in 1 of 14 identified …

Abstract Background RNA sequencing (RNA-Seq) in its varied forms has become an
indispensable tool for analyzing differential gene expression and thus characterization of …

The telomerase reverse transcriptase gene (TERT) encodes the reverse transcriptase
component of the telomerase complex, which is essential for telomere stabilization and cell …

Many factors affect the integrity of messenger RNA from human autopsy tissues including
postmortem interval (PMI) between death and tissue preservation and the pre-mortem …

Background: It is widely assumed that the integrity of tissue specimens remains stable
indefinitely if preserved at cryogenic temperatures. With biobanking reaching a level of …

Schizophrenia is a complex neurodevelopmental disorder with high rate of morbidity and
mortality. While the heritability rate is high, the precise etiology is still unknown. Although …

Cryopreservation of biological materials is predominantly done using liquid nitrogen, and its
application involves high maintenance costs and the need for periodical refilling of liquid …

Human biorepositories are collection of biological samples and health information from a
large number of participants generally in the cohort studies. The main purpose of …