Polymer-based nanomaterials and applications for vaccines and drugs

J Han, D Zhao, D Li, X Wang, Z Jin, K Zhao - Polymers, 2018 - mdpi.com
Nanotechnology plays a significant role in drug development. As carriers, polymeric
nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action …

Prodigiosin: A promising biomolecule with many potential biomedical applications

GA Islan, B Rodenak-Kladniew, N Noacco… - …, 2022 - Taylor & Francis
Pigments are among the most fascinating molecules found in nature and used by human
civilizations since the prehistoric ages. Although most of the bio-dyes reported in the …

Drug-encapsulated blend of PLGA-PEG microspheres: in vitro and in vivo study of the effects of localized/targeted drug delivery on the treatment of triple-negative …

SM Jusu, JD Obayemi, AA Salifu, CC Nwazojie… - Scientific Reports, 2020 - nature.com
Triple-negative breast cancer (TNBC) is more aggressive and difficult to treat using
conventional bulk chemotherapy that is often associated with increased toxicity and side …

Advancing PHBV biomedical potential with the incorporation of bacterial biopigment prodigiosin

M Ponjavic, I Malagurski, J Lazic, S Jeremic… - International Journal of …, 2023 - mdpi.com
The quest for sustainable biomaterials with excellent biocompatibility and tailorable
properties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high …

Anomalous release kinetics of prodigiosin from poly-N-isopropyl-acrylamid based hydrogels for the treatment of triple negative breast cancer

Y Danyuo, CJ Ani, AA Salifu, JD Obayemi… - Scientific reports, 2019 - nature.com
This paper presents the anomalous release kinetics of a cancer drug (prodigiosin) frompoly-
n-isopropyl-acrylamide (P (NIPA))-based gels. The release exponents, n, which correspond …

Recent advances in prodigiosin as a bioactive compound in nanocomposite applications

RG Araújo, NR Zavala, C Castillo-Zacarías, ME Barocio… - Molecules, 2022 - mdpi.com
Bionanocomposites based on natural bioactive entities have gained importance due to their
abundance; renewable and environmentally benign nature; and outstanding properties with …

Degradable porous drug-loaded polymer scaffolds for localized cancer drug delivery and breast cell/tissue growth

JD Obayemi, SM Jusu, AA Salifu, S Ghahremani… - Materials Science and …, 2020 - Elsevier
This paper presents the results of a combined experimental and analytical study of blended
FDA-approved polymers [polylactic-co-glycolic acid (PLGA), polyethylene glycol (PEG) and …

Recent advances in novel drug delivery systems and approaches for management of breast cancer: A comprehensive review

U Hani, M Rahamathulla, RA Osmani, HY Kumar… - Journal of Drug Delivery …, 2020 - Elsevier
Breast Cancer (BC) is a carcinoma of breast tissues, the major recurrent cancer in women
and also the foremost cause of death with approximate 5 million annual deaths worldwide …

Prodigiosin-loaded electrospun nanofibers scaffold for localized treatment of triple negative breast cancer

UM Akpan, M Pellegrini, JD Obayemi… - Materials Science and …, 2020 - Elsevier
Hybrid composite nanofibers, with the potential to enhance cell adhesion while improving
sustained drug release profiles, were fabricated by the blend electrospinning of poly (d, l …

Extraction and encapsulation of prodigiosin in chitosan microspheres for targeted drug delivery

SO Dozie-Nwachukwu, Y Danyuo, JD Obayemi… - Materials Science and …, 2017 - Elsevier
The encapsulation of drugs in polymeric materials has brought opportunities to the targeted
delivery of chemotherapeutic agents. These polymeric delivery systems are capable of …