Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis

H Kelly, Y Benavente, MA Pavon, S De Sanjose… - British journal of …, 2019 - nature.com
Background To conduct a meta-analysis of performance of DNA methylation in women with
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …

DNA methylation and hydroxymethylation in cervical cancer: diagnosis, prognosis and treatment

H Zhu, H Zhu, M Tian, D Wang, J He, T Xu - Frontiers in Genetics, 2020 - frontiersin.org
Recent discoveries have led to the development of novel ideas and techniques that have
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …

Performance of a DNA methylation marker panel using liquid-based cervical scrapes to detect cervical cancer and its precancerous stages

M Schmitz, K Eichelkraut, D Schmidt, I Zeiser, Z Hilal… - BMC cancer, 2018 - Springer
Background A change of cervical cancer screening algorithms to an HPV-based screening
setting is discussed in many countries, due to higher sensitivity of HPV testing compared to …

Triage performance of PAX1m/JAM3m in opportunistic cervical cancer screening of non‒16/18 human papillomavirus-positive women: a multicenter prospective …

X Chen, X Jin, L Kong, Y Liou, P Liu, Z Dong, S Zhou… - Clinical …, 2024 - Springer
Objectives In this study, we aimed to validate the performance of the PAX1 and JAM3
methylation (PAX1 m/JAM3 m) test as a triage tool for detecting cervical intraepithelial …

Cervical cancer, geographical inequalities, prevention and barriers in resource depleted countries

A Bogdanova, C Andrawos… - Oncology …, 2022 - spandidos-publications.com
Cervical cancer (CC) remains a current global issue, with> 90% of cervical cancer cases
being attributed to human papilloma virus (HPV). The highest burden of cervical cancer is …

Epigenetic approaches for cervical neoplasia screening

A Albulescu, A Plesa, A Fudulu… - Experimental and …, 2021 - spandidos-publications.com
Human papillomavirus (HPV) infection is the leading cause of cervical cancer. The
Papanicolaou cytology test is the usually employed type of screening for this infection; …

Performance of a methylation specific real-time PCR assay as a triage test for HPV-positive women

M Schmitz, K Wunsch, H Hoyer, C Scheungraber… - Clinical …, 2017 - Springer
Background HPV DNA testing as a primary screening marker is being implemented in
several countries. Due to the high HPV prevalence in the screening population, effective …

The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre) cancer in Chinese women

Q Bu, S Wang, J Ma, X Zhou, G Hu, H Deng, X Sun… - Bmc Cancer, 2018 - Springer
Background To explore the diagnostic value of FAM19A4 methylation in high-risk human
papilloma virus (hrHPV)-positive cervical samples from Chinese women for estimating …

DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population

N Li, Y Hu, X Zhang, Y Liu, Y He… - … journal of cancer, 2021 - Wiley Online Library
Objective strategies are required in cervical cancer screening. We have identified several
DNA methylation markers with high sensitivity and specificity to detect cervical intraepithelial …

Detection of DNA methylation in gene loci ASTN1, DLX1, ITGA4, RXFP3, SOX17, and ZNF671 for diagnosis of cervical cancer

C Fan, Q Ma, X Wu, X Dai, Q Peng… - Cancer Management and …, 2023 - Taylor & Francis
Objective To evaluate the diagnostic value of DNA methylation detection of multiple gene
loci in cervical cancer. Methods A total of 61 cases requiring cervical biopsy were selected …