Adipokine dysregulation and adipose tissue inflammation in human obesity
X Unamuno, J Gómez‐Ambrosi… - European journal of …, 2018 - Wiley Online Library
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
Relevance of leptin and other adipokines in obesity-associated cardiovascular risk
MF Landecho, C Tuero, V Valentí, I Bilbao… - Nutrients, 2019 - mdpi.com
Obesity, which is a worldwide epidemic, confers increased risk for multiple serious
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …
conditions including type 2 diabetes, nonalcoholic fatty liver disease, and cardiovascular …
NLRP3 inflammasome blockade reduces adipose tissue inflammation and extracellular matrix remodeling
X Unamuno, J Gómez-Ambrosi, B Ramírez… - Cellular & molecular …, 2021 - nature.com
Abstract The NLRP3-IL-1β pathway plays an important role in adipose tissue (AT)-induced
inflammation and the development of obesity-associated comorbidities. We aimed to …
inflammation and the development of obesity-associated comorbidities. We aimed to …
Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker
GA Baselli, P Dongiovanni, R Rametta, M Meroni… - Gut, 2020 - gut.bmj.com
Objective Efforts to manage non-alcoholic fatty liver disease (NAFLD) are limited by the
incomplete understanding of the pathogenic mechanisms and the absence of accurate non …
incomplete understanding of the pathogenic mechanisms and the absence of accurate non …
Therapeutic landscape of metabolic dysfunction-associated steatohepatitis (MASH)
Metabolic dysfunction-associated steatotic liver disease (MASLD) and its severe subgroup
metabolic dysfunction-associated steatohepatitis (MASH) have become a global epidemic …
metabolic dysfunction-associated steatohepatitis (MASH) have become a global epidemic …
Molecular interactions and functions of IL-32
IL-32 is a multifaceted cytokine associated with several diseases and inflammatory
conditions. Its expression is induced in response to cellular stress such as hypoxia …
conditions. Its expression is induced in response to cellular stress such as hypoxia …
[HTML][HTML] Genetic predisposition similarities between NASH and ASH: identification of new therapeutic targets
C Bianco, E Casirati, F Malvestiti, L Valenti - JHEP Reports, 2021 - Elsevier
Fatty liver disease can be triggered by a combination of excess alcohol, dysmetabolism and
other environmental cues, which can lead to steatohepatitis and can evolve to acute/chronic …
other environmental cues, which can lead to steatohepatitis and can evolve to acute/chronic …
Physiological changes and pathological pain associated with sedentary lifestyle-induced body systems fat accumulation and their modulation by physical exercise
E Verdú, J Homs, P Boadas-Vaello - International journal of …, 2021 - mdpi.com
A sedentary lifestyle is associated with overweight/obesity, which involves excessive fat
body accumulation, triggering structural and functional changes in tissues, organs, and body …
body accumulation, triggering structural and functional changes in tissues, organs, and body …
Abdominal subcutaneous adipose tissue: a favorable adipose depot for diabetes?
P Chen, X Hou, G Hu, L Wei, L Jiao, H Wang… - Cardiovascular …, 2018 - Springer
Background Previous studies have documented that visceral adipose tissue is positively
associated with the risk of diabetes. However, the association of subcutaneous adipose …
associated with the risk of diabetes. However, the association of subcutaneous adipose …