The orphan nuclear receptor steroidogenic factor 1 (SF-1, also called Ad4BP, encoded by
the NR5A1 gene) is an essential regulator of endocrine development and function. Initially …

Steroidogenic factor 1 (SF-1, also called Ad4BP and NR5A1) is a nuclear receptor with
critical roles in steroidogenic tissues, as well as in the brain and pituitary. In particular, SF-1 …

Histone acetyltransferases and deacetylases are recruited by transcription factors and
adapter proteins to regulate specific subsets of target genes. We were interested in …

In this study, we have investigated the role of C‐terminal binding proteins (CtBPs) and
histone deacetylases (HDACs) in the repressive activity of the nuclear receptor cofactor …

Infertility has attracted global concern, and disruption of testosterone is a common cause of
male infertility. Exploring the critical factors in testosterone biosynthesis may provide new …

Excess androgen synthesis by thecal cells is invariably detrimental to preovulatory follicles
in the ovary and considered a fundamental characteristic of polycystic ovary syndrome in …

Steroidogenic factor-1 (SF-1), has emerged as a critical nuclear receptor regulating
development and differentiation at several levels of the hypothalamic-pituitary-steroidogenic …

The DEAD-box helicase DP103 (Ddx20, Gemin3) is a multifunctional protein that interacts
with Epstein-Barr virus nuclear proteins (EBNA2/EBNA3) and is a part of the spliceosomal …

Scaffold attachment factor-B1 (SAFB1) is a nuclear matrix protein that has been proposed to
couple chromatin structure, transcription, and RNA processing. We have previously shown …

The thyroid hormone receptor regulates a diverse set of genes that control processes from
embryonic development to adult homeostasis. Upon binding of thyroid hormone, the thyroid …