Multiple roles of chitosan in mucosal drug delivery: an updated review

P Mura, F Maestrelli, M Cirri, N Mennini - Marine Drugs, 2022 - mdpi.com
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after
cellulose, is the second biopolymer most abundant in nature, being the primary component …

Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

Reduced polydopamine nanoparticles incorporated oxidized dextran/chitosan hybrid hydrogels with enhanced antioxidative and antibacterial properties for …

Y Fu, J Zhang, Y Wang, J Li, J Bao, X Xu, C Zhang… - Carbohydrate …, 2021 - Elsevier
Hydrogels with antioxidative and antibacterial properties have emerged as potential
dressings for accelerated wound healing. Herein, a series of reduced polydopamine …

Preparation, characterization and antioxidant activity of protocatechuic acid grafted carboxymethyl chitosan and its hydrogel

C Xu, S Guan, J Xu, W Gong, T Liu, X Ma, C Sun - Carbohydrate Polymers, 2021 - Elsevier
In this study, protocatechuic acid (PCA) was grafted onto carboxymethyl chitosan (CMCS)
via EDC/NHS to improve the antioxidant effect. The grafting ratio of PCA-g-CMCS …

Electrospun polyvinylpyrrolidone (PVP) hydrogels containing hydroxycinnamic acid derivatives as potential wound dressings

M Contardi, D Kossyvaki, P Picone, M Summa… - Chemical Engineering …, 2021 - Elsevier
Polyvinylpyrrolidone (commonly known as povidone or PVP) rapidly dissolves in water. This
significantly hinders its use in sustained release formulations developed for the biomedical …

Corneal repair and regeneration: current concepts and future directions

M Mobaraki, R Abbasi, S Omidian Vandchali… - … in Bioengineering and …, 2019 - frontiersin.org
The cornea is a unique tissue and the most powerful focusing element of the eye, known as
a window to the eye. Infectious or non-infectious diseases might cause severe visual …

Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications

KA Soliman, K Ullah, A Shah, DS Jones… - Drug Discovery …, 2019 - Elsevier
Highlights•Poloxamers-based in situ gels are potential vehicles for ocular drug
delivery.•Poloxamers possess reversible thermoresponsive gelling and mucoadhesive …

Hydrogels as emerging materials for cornea wound healing

S Khosravimelal, M Mobaraki, S Eftekhari, M Ahearne… - Small, 2021 - Wiley Online Library
Hydrogel biomaterials have many favorable characteristics including tuneable mechanical
behavior, cytocompatibility, optical properties suitable for regeneration and restoration of the …

Influence of chitosan oligosaccharide on the gelling and wound healing properties of injectable hydrogels based on carboxymethyl chitosan/alginate polyelectrolyte …

X Lv, Y Liu, S Song, C Tong, X Shi, Y Zhao… - Carbohydrate …, 2019 - Elsevier
In situ injectable hydrogels for wound healing based on carboxymethyl chitosan (CMCS)
and alginate were developed in this work. The liquid mixture of CMCS and alginate …

Chitosan-based in situ gels for ocular delivery of therapeutics: a state-of-the-art review

T Irimia, CE Dinu-Pîrvu, MV Ghica, D Lupuleasa… - Marine drugs, 2018 - mdpi.com
Ocular in situ gels are a promising alternative to overcome drawbacks of conventional eye
drops because they associate the advantages of solutions such as accuracy and …