Diet has a pivotal role in shaping the composition, function and diversity of the gut
microbiome, with various diets having a profound impact on the stability, functionality and …

Azo compounds are widely distributed synthetic chemicals in the modern world. Their most
important applications are as dyes, but, in addition, several azo compounds are used as …

Allergic diseases affect millions of people worldwide. An increase in their prevalence has
been associated with alterations in the gut microbiome, ie, the microorganisms and their …

Drugs represent our first, and sometimes last, line of defense for many diseases, yet despite
decades of research we still do not fully understand why a given drug works in one patient …

Abstract Tartrazine (E102, FD&C Yellow 5) is a vibrant yellow azo dye added to many
processed foods. The safety of this ubiquitous chemical has not been fully elucidated, and it …

Prodrugs reliant on microbial activation are widely used but exhibit a range of efficacies that
remain poorly understood. The anti-inflammatory compound 5-aminosalicylic acid (5-ASA) …

Sulfide ions are regarded to be toxic to microorganisms in engineered methanogenic
systems (EMS), where organic substances are anaerobically converted to products such as …

Gut microbiome plays a vital role in the intestinal ecosystem and has close association with
metabolites. Due to the development of metabolomics and microbiomics, recent studies …

Background H2S imbalances in the intestinal tract trigger Crohn's disease (CD), a chronic
inflammatory gastrointestinal disorder characterized by microbiota dysbiosis and barrier …

Humans are exposed to a wide variety of small molecules with antioxidant properties that
are poorly metabolized by mammalian cells. However, gastrointestinal microbes encode …