Revisiting the neurovascular unit
S Schaeffer, C Iadecola - Nature neuroscience, 2021 - nature.com
The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
Neuroinflammation as a key driver of secondary neurodegeneration following stroke?
SM Stuckey, LK Ong, LE Collins-Praino… - International Journal of …, 2021 - mdpi.com
Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …
The role of inflammasomes in vascular cognitive impairment
There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …
Acupuncture Attenuates Inflammation in Microglia of Vascular Dementia Rats by Inhibiting miR‐93‐Mediated TLR4/MyD88/NF‐κB Signaling Pathway
L Wang, JW Yang, LT Lin, J Huang… - Oxidative Medicine …, 2020 - Wiley Online Library
Background. It is widely accepted that inflammation may contribute to cognitive impairment
in patients with vascular dementia (VD). Our prior clinical researches have reported that …
in patients with vascular dementia (VD). Our prior clinical researches have reported that …
Role of inflammatory markers in the diagnosis of vascular contributions to cognitive impairment and dementia: a systematic review and meta-analysis
C Custodero, A Ciavarella, F Panza, D Gnocchi… - Geroscience, 2022 - Springer
Vascular contribution to cognitive impairment and dementia (VCID) is a clinical label
encompassing a wide range of cognitive disorders progressing from mild to major vascular …
encompassing a wide range of cognitive disorders progressing from mild to major vascular …
Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment
Vascular cognitive impairment (VCI) describes a wide spectrum of cognitive deficits related
to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically …
to cerebrovascular diseases. Although the loss of blood flow to cortical regions critically …
[HTML][HTML] Measuring gait speed to better identify prodromal dementia
Slow gait speed has been shown to predict incident dementia and cognitive decline in older
individuals. We aimed to summarize the evidence concerning the association of slow gait …
individuals. We aimed to summarize the evidence concerning the association of slow gait …
[HTML][HTML] Upregulation of neuronal PGC-1α ameliorates cognitive impairment induced by chronic cerebral hypoperfusion
B Han, W Jiang, H Liu, J Wang, K Zheng, P Cui… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Mitochondrial dysfunction and oxidative stress occur in vascular dementia (VaD),
but the specific molecular mechanism regulating these events remains unclear. Peroxisome …
but the specific molecular mechanism regulating these events remains unclear. Peroxisome …
Association of pro-inflammatory diet with increased risk of all-cause dementia and Alzheimer's dementia: a prospective study of 166,377 UK Biobank participants
Y Shi, F Lin, Y Li, Y Wang, X Chen, F Meng, Q Ye… - BMC medicine, 2023 - Springer
Background Increasing evidence suggests an association between pro-inflammatory diets
and cognitive function. However, only a few studies based on small sample sizes have …
and cognitive function. However, only a few studies based on small sample sizes have …
Time-dependent dual effect of microglia in ischemic stroke
P Fan, S Wang, S Chu, N Chen - Neurochemistry international, 2023 - Elsevier
Stroke, the third leading cause of death and disability worldwide, is classified into ischemic
or hemorrhagic, in which approximately 85% of strokes are ischemic. Ischemic stroke occurs …
or hemorrhagic, in which approximately 85% of strokes are ischemic. Ischemic stroke occurs …