Context.—The unprecedented advances in cancer genetics and genomics are rapidly
affecting clinical management and diagnostics in solid tumor oncology. Molecular …

To perform a feature analysis of malignant renal tumors evaluated with magnetic resonance
(MR) imaging and to investigate the correlation between MR imaging features and …

Compared to other solid tumours such as breast, colon, and lung, the current clinical
management of urological malignancies is lagging behind in terms of utilisation of clinically …

Background The role of angiogenesis in the pathogenesis of renal cell carcinoma is well
recognized, however, the influence of tumor cells in this activity has not yet been fully …

Background The ability of aggressive tumors to form nonendothelial tumor cell-lined
microvascular channels is known as" vasculogenic mimicry"(VM). VM channels are revealed …

Previous studies have shown that interleukin-17F (IL-17F) can markedly inhibit the
angiogenesis of endothelial cells, implying that it may play a role in antiangiogenic therapy …

Renal cell carcinoma (RCC) represents around 3% of all cancers, with the most frequent
histological types being clear-cell RCC (ccRCC), followed by papillary (pRCC) and …

Primary renal cell carcinomas (pRCCs) have a high degree of intratumoral heterogeneity
and are composed of multiple distinct subclones. However, it remains largely unknown that …

The course of RCC is asymptomatic, resulting in 25-30% of patients presenting with
metastatic disease at time of diagnosis. The development of novel agents targeting …

OBJECTIVES: To investigate the relationship between angiogenesis and coagulation
markers in tumor tissues of primary renal cell carcinoma (RCC). Tumors stimulate …