Cu homeostasis in bacteria: the ins and outs

A Andrei, Y Öztürk, B Khalfaoui-Hassani, J Rauch… - Membranes, 2020 - mdpi.com
Copper (Cu) is an essential trace element for all living organisms and used as cofactor in
key enzymes of important biological processes, such as aerobic respiration or superoxide …

P-type ATPases: Many more enigmas left to solve

M Palmgren - Journal of Biological Chemistry, 2023 - ASBMB
P-type ATPases constitute a large ancient super-family of primary active pumps that have
diverse substrate specificities ranging from H+ to phospholipids. The significance of these …

Evolution of Listeria monocytogenes in a food processing plant involves limited single-nucleotide substitutions but considerable diversification by gain and loss of …

AS Harrand, B Jagadeesan, L Baert… - Applied and …, 2020 - Am Soc Microbiol
Whole-genome sequencing (WGS) is becoming the standard method for subtyping Listeria
monocytogenes. Interpretation of WGS data for isolates from foods and associated …

Fast-forward on P-type ATPases: recent advances on structure and function

C Stock, T Heger, S Basse Hansen… - Biochemical Society …, 2023 - portlandpress.com
P-type ATPase are present in nearly all organisms. They maintain electrochemical gradients
for many solutes, in particular ions, they control membrane lipid asymmetry, and are crucial …

Structural basis of ion uptake in copper-transporting P1B-type ATPases

N Salustros, C Grønberg, NS Abeyrathna, P Lyu… - Nature …, 2022 - nature.com
Copper is essential for living cells, yet toxic at elevated concentrations. Class 1B P-type
(P1B-) ATPases are present in all kingdoms of life, facilitating cellular export of transition …

Unraveling the role of metals and organic acids in bacterial antimicrobial resistance in the food chain

A Rebelo, A Almeida, L Peixe, P Antunes, C Novais - Antibiotics, 2023 - mdpi.com
Antimicrobial resistance (AMR) has a significant impact on human, animal, and
environmental health, being spread in diverse settings. Antibiotic misuse and overuse in the …

Bacterial Metallostasis: Metal Sensing, Metalloproteome Remodeling, and Metal Trafficking

DA Capdevila, JJ Rondón, KA Edmonds… - Chemical …, 2024 - ACS Publications
Transition metals function as structural and catalytic cofactors for a large diversity of proteins
and enzymes that collectively comprise the metalloproteome. Metallostasis considers all …

Unveiling the Dual Nature of Heavy Metals: Stressors and Promoters of Phenolic Compound Biosynthesis in Basilicum polystachyon (L.) Moench In Vitro

S Das, KW Sultana, M Mondal, I Chandra, AR Ndhlala - Plants, 2023 - mdpi.com
The global industrial revolution has led to a substantial rise in heavy metal levels in the
environment, posing a serious threat to nature. Plants synthesize phenolic compounds …

Phytochemical analysis, cellular antioxidant and α-glucosidase inhibitory activities of various herb plant organs

Y Chen, E Wang, Z Wei, Y Zheng, R Yan… - Industrial Crops and …, 2019 - Elsevier
Herb plant organs are aboundant in phytochemicals and possess multiple bioactivities.
Investigation in the phytochemicals of herb plants organs and associated functionalities …

Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases

Z Guo, F Orädd, V Bågenholm, C Grønberg… - Nature …, 2024 - nature.com
Copper transporting P-type (P1B-1-) ATPases are essential for cellular homeostasis.
Nonetheless, the E1-E1P-E2P-E2 states mechanism of P1B-1-ATPases remains poorly …