Human hemoglobin genes are located in α and β globin gene clusters in chromosomes 16
and 11, respectively. Different types of hemoglobin are synthesized according to the stage of …

Hb E-β-thalassemia is the most common form of β-thalassemia found in Thailand. The
disease exhibits a varied clinical expression ranging from severe transfusion dependence to …

Background and aims High hemoglobin F determinants can be classified into hereditary
persistence of fetal hemoglobin (HPFH) and δβ-thalassemia with different phenotype. We …

Study on the phenotypic expression of hemoglobin (Hb) A2 and Hb E in Hb E disorders has
been difficult due to the co-separation of Hb A2 and Hb E in most Hb analysis assays …

Background β 0-thalassemia deletion removing 5 β-globin promoter usually presents
phenotype with high hemoglobin (Hb) A 2 and Hb F levels. We report the molecular …

Objective To reveal the prevalence and molecular characterization of (δβ) 0‐thalassemia
[(δβ) 0‐thal] and hereditary persistence of fetal hemoglobin (HPFH) in the Chinese Zhuang …

Background and Aims: A pilot screening program for thalassemia was initiated in the Lao
People's Democratic Republic. This study aimed to describe the genotype diversity and …

Background Deletions of δ‐and β‐globin genes are associated with different H b F levels. To
address this, we have examined hematological and molecular characteristics in a large …

Objective To report the phenotypes and genetic basis of a novel A γδβ 0-thalassemia found
in Thai individuals with several forms of thalassemia. Designs and methods An initial study …

δβ-Thalassemia (δβ-thal) and hereditary persistence of fetal hemoglobin (HPFH) are
heterogeneous disorders characterized by elevated levels of Hb F in adult life. The two …