Advances in biomedical Raman microscopy
KA Antonio, ZD Schultz - Analytical chemistry, 2014 - ACS Publications
The vibrational modes of molecules provide an intrinsic contrast mechanism for identifying
components in cells, tissues, and organisms. When excited by a laser, Raman scattered …
components in cells, tissues, and organisms. When excited by a laser, Raman scattered …
Histological coherent Raman imaging: a prognostic review
MT Cicerone, CH Camp - Analyst, 2018 - pubs.rsc.org
Histopathology plays a central role in diagnosis of many diseases including solid cancers.
Efforts are underway to transform this subjective art to an objective and quantitative science …
Efforts are underway to transform this subjective art to an objective and quantitative science …
Hyperspectral and differential CARS microscopy for quantitative chemical imaging in human adipocytes
In this work, we demonstrate the applicability of coherent anti-Stokes Raman scattering
(CARS) micro-spectroscopy for quantitative chemical imaging of saturated and unsaturated …
(CARS) micro-spectroscopy for quantitative chemical imaging of saturated and unsaturated …
Quantitative 3D molecular cutaneous absorption in human skin using label free nonlinear microscopy
X Chen, S Grégoire, F Formanek, JB Galey… - Journal of Controlled …, 2015 - Elsevier
Understanding the penetration mechanisms of drugs into human skin is a key issue in
pharmaceutical and cosmetics research. To date, the techniques available for percutaneous …
pharmaceutical and cosmetics research. To date, the techniques available for percutaneous …
Amplitude and polarization modulated hyperspectral stimulated Raman scattering microscopy
We present a simple hyperspectral Stimulated Raman Scattering (SRS) microscopy method
based on spectral focusing of chirped femtosecond pulses, combined with amplitude (AM) …
based on spectral focusing of chirped femtosecond pulses, combined with amplitude (AM) …
Rapid 3D chemical‐specific imaging of minerals using stimulated Raman scattering microscopy
MA Houle, RC Burruss, A Ridsdale… - Journal of Raman …, 2017 - Wiley Online Library
Raman microscopy, which offers chemical‐specific imaging, has important applications in
geological sciences. Conventional Raman imaging, however, is challenged by long …
geological sciences. Conventional Raman imaging, however, is challenged by long …
Hyperspectral volumetric coherent anti‐Stokes Raman scattering microscopy: quantitative volume determination and NaCl as non‐resonant standard
In this work, we demonstrate quantitative volume determination of chemical components in
three dimensions using hyperspectral coherent anti‐Stokes Raman scattering microscopy …
three dimensions using hyperspectral coherent anti‐Stokes Raman scattering microscopy …
Direct visualization of the arterial wall water permeability barrier using CARS microscopy
BM Lucotte, C Powell, JR Knutson… - Proceedings of the …, 2017 - National Acad Sciences
The artery wall is equipped with a water permeation barrier that allows blood to flow at high
pressure without significant water leak. The precise location of this barrier is unknown …
pressure without significant water leak. The precise location of this barrier is unknown …
Effects of refractive index mismatch on SRS and CARS microscopy
An inhomogeneous linear refractive index profile, such as that occurring in biological
tissues, is shown to significantly alter stimulated Raman scattering (SRS) and coherent anti …
tissues, is shown to significantly alter stimulated Raman scattering (SRS) and coherent anti …
Impact of refractive index mismatches on coherent anti-Stokes Raman scattering and multiphoton autofluorescence tomography of human skin in vivo
M Weinigel, HG Breunig, ME Darvin… - Physics in Medicine …, 2015 - iopscience.iop.org
Optical non-linear multimodal tomography is a powerful diagnostic imaging tool to analyse
human skin based on its autofluorescence and second-harmonic generation signals …
human skin based on its autofluorescence and second-harmonic generation signals …