Targeting mitochondria in Cancer therapy: Machine learning analysis of hyaluronic acid-based drug delivery systems

GN Iaconisi, A Ahmed, G Lauria, N Gallo… - International Journal of …, 2024 - Elsevier
Background Mitochondrial alterations play a crucial role in the development and
progression of cancer. Dysfunctional mitochondria contribute to the acquisition of key …

A chitosan-camouflaged nanomedicine triggered by hierarchically stimuli to release drug for multimodal imaging-guided chemotherapy of breast cancer

P Wang, Z Peng, Y Zhang, X Zhang, X Chen, F Li… - Carbohydrate …, 2024 - Elsevier
Breast cancer remains one of the most intractable diseases, especially the malignant form of
metastasis, with which the cancer cells are hard to track and eliminate. Herein, the common …

NIR-triggered arsenic-loaded layered double hydroxide-based films for localized thermal synergistic chemotherapy

S Xing, H Zhang, Z Hou, F Peng, L Liu, D Wang… - Journal of Colloid and …, 2024 - Elsevier
Portal vein tumor thrombus (PVTT) formed by cancer cell invasion is a major cause of high
mortality in hepatocellular carcinoma (HCC), and the formation of thrombus will be …

Fabrication of co-delivery liposomal formulation incorporating carmustine and cabazitaxel displays improved cytotoxic potential and induced apoptosis in ovarian …

J Gong, R Feng, X Fu, Q Lin, B Wu - Journal of Biomaterials …, 2024 - Taylor & Francis
Ovarian cancer is the primary cause of death from cancer in female patients. The existing
treatments for ovarian cancer are restricted and ineffective in achieving a cure for the …

Detection of Nanoparticle-Mediated Change in Mitochondrial Membrane Potential in T Cells Using JC-1 Dye

A Shah, MA Dobrovolskaia - … of Nanoparticles Intended for Drug Delivery, 2024 - Springer
Alterations in mitochondrial membrane potential are associated with the generation of
reactive oxygen species and cell death. While eliminating cancer cells is beneficial for …