Sudden unexpected death in epilepsy: mechanisms, prevalence, and prevention

R Surges, JW Sander - Current opinion in neurology, 2012 - journals.lww.com
Novel clinical features may help to define better the individual risk of SUDEP. Potentially
therapeutic strategies including pharmacological modulation of respiratory arrest and …

Who to target in sudden unexpected death in epilepsy prevention and how? Risk factors, biomarkers, and intervention study designs

T Tomson, R Surges, R Delamont, S Haywood… - …, 2016 - Wiley Online Library
The risk of dying suddenly and unexpectedly is increased 24‐to 28‐fold among young
people with epilepsy compared to the general population, but the incidence of sudden …

Identifying patients with epilepsy at high risk of cardiac death: signs, risk factors and initial management of high risk of cardiac death

R Surges, S Shmuely, C Dietze, P Ryvlin… - Epileptic …, 2021 - Wiley Online Library
People with epilepsy have a three‐fold increased risk of dying prematurely, and a significant
proportion is due to sudden cardiac death or acute myocardial infarctions. The causes of …

Too long or too short? New insights into abnormal cardiac repolarization in people with chronic epilepsy and its potential role in sudden unexpected death

R Surges, P Taggart, JW Sander, MC Walker - Epilepsia, 2010 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is probably caused by periictal
cardiorespiratory alterations such as central apnea, bradyarrhythmia, and neurogenic …

Epilepsy is a risk factor for sudden cardiac arrest in the general population

A Bardai, RJ Lamberts, MT Blom, AM Spanjaart… - 2012 - journals.plos.org
Background People with epilepsy are at increased risk for sudden death. The most prevalent
cause of sudden death in the general population is sudden cardiac arrest (SCA) due to …

The pathophysiology of cardiac dysfunction in epilepsy

K Ravindran, KL Powell, M Todaro, TJ O'Brien - Epilepsy research, 2016 - Elsevier
Alterations in cardiac electrophysiology are an established consequence of long-standing
drug resistant epilepsy. Patients with chronic epilepsy display abnormalities in both …

Comorbidity between epilepsy and cardiac arrhythmias: implication for treatment

G Zaccara, S Lattanzi - Epilepsy & Behavior, 2019 - Elsevier
Epilepsy is often comorbid with either neurological or nonneurological diseases. The
association between epilepsy and cardiac arrhythmias is not infrequent, mostly in patients …

Individuals with chronic epilepsy have elevated P‐wave heterogeneity comparable to patients with atrial fibrillation

GL Fialho, TD Pang, WY Kong, AP Tran, CG Yu… - …, 2023 - Wiley Online Library
Objective Identification of epilepsy patients with elevated risk for atrial fibrillation (AF) is
critical given the heightened morbidity and premature mortality associated with this …

Cardiac arrhythmias and sudden unexpected death in epilepsy (SUDEP)

P Velagapudi, M Turagam, T Laurence… - Pacing and clinical …, 2012 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is a major clinical problem in epilepsy
patients in the United States, especially those with chronic, uncontrolled epilepsy. Several …

Increased prevalence of ECG markers for sudden cardiac arrest in refractory epilepsy

RJ Lamberts, MT Blom, J Novy, M Belluzzo… - Journal of Neurology …, 2015 - jnnp.bmj.com
Background and aim People with epilepsy are at increased risk of sudden cardiac arrest
(SCA) due to ECG-confirmed ventricular tachycardia/fibrillation, as seen in a community …