Sulfhydryl groups as targets of mercury toxicity
The present study addresses existing data on the affinity and conjugation of sulfhydryl (thiol;-
SH) groups of low-and high-molecular-weight biological ligands with mercury (Hg). The …
SH) groups of low-and high-molecular-weight biological ligands with mercury (Hg). The …
[HTML][HTML] Methylmercury's chemistry: From the environment to the mammalian brain
Methylmercury is a neurotoxicant that is found in fish and rice. MeHg's toxicity is mediated by
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …
blockage of-SH and-SeH groups of proteins. However, the identification of MeHg's targets is …
Diphenyl Diselenide and SARS-CoV-2: in silico Exploration of the Mechanisms of Inhibition of Main Protease (Mpro) and Papain-like Protease (PLpro)
FB Omage, A Madabeni, AR Tucci… - Journal of Chemical …, 2023 - ACS Publications
The SARS-CoV-2 pandemic has prompted global efforts to develop therapeutics. The main
protease of SARS-CoV-2 (Mpro) and the papain-like protease (PLpro) are essential for viral …
protease of SARS-CoV-2 (Mpro) and the papain-like protease (PLpro) are essential for viral …
Mercury and prenatal growth: a systematic review
The intrauterine environment is critical for healthy prenatal growth and affects neonatal
survival and later health. Mercury is a toxic metal which can freely cross the placenta and …
survival and later health. Mercury is a toxic metal which can freely cross the placenta and …
Exposure to thimerosal induces behavioral abnormality in the early life stages of zebrafish via altering amino acid homeostasis
X Qiu, Y Zhang, J Gao, Y Cui, K Dong, K Chen… - Journal of Hazardous …, 2024 - Elsevier
Thimerosal (THI) has become a significant source of organic mercury pollutants in aquatic
ecosystems, but there is limited information regarding its adverse effects on fish. In this …
ecosystems, but there is limited information regarding its adverse effects on fish. In this …
Prenatal mercury exposure and neurodevelopment up to the age of 5 years: A systematic review
Neurodevelopmental delays can interfere with children's engagement with the world and
further development, and may have negative consequences into adulthood. Mercury is …
further development, and may have negative consequences into adulthood. Mercury is …
Toxicological Effects of Thimerosal and Aluminum in the Liver, Kidney, and Brain of Zebrafish (Danio rerio)
MEA Galiciolli, JF Silva, MM Prodocimo, HA Laureano… - Metabolites, 2023 - mdpi.com
Vaccination programs in the first years of a child's life are effective and extremely important
strategies for the successful eradication of diseases. However, as no intervention is without …
strategies for the successful eradication of diseases. However, as no intervention is without …
Toxic metals that interact with thiol groups and alteration in insect behavior
CS Oliveira, PA Nogara, LS Lima, MEA Galiciolli… - Current Opinion in Insect …, 2022 - Elsevier
Highlights•Toxic metals (TM) are ubiquitous, and insects are susceptible to
contamination.•TM mechanism of toxicity in insects is related to interaction with–SH …
contamination.•TM mechanism of toxicity in insects is related to interaction with–SH …
Organic selenocompounds: are they the panacea for human illnesses?
The selenium element is essential to some life forms and its biological-chemistry function is
mainly performed by the selenol/selenolate moiety (–SeH/–Se–) in a few selenoproteins …
mainly performed by the selenol/selenolate moiety (–SeH/–Se–) in a few selenoproteins …
Neurotoxic effects of combined exposures to aluminum and mercury in early life (infancy)
JG Dórea - Environmental Research, 2020 - Elsevier
Aluminum and mercury are environmentally ubiquitous. Individually they are both neurotoxic
elements with shared neuro-pathogenic pathways: oxidative stress, altered …
elements with shared neuro-pathogenic pathways: oxidative stress, altered …