The interplay between diet, the gut microbiome, and host health is complex. Diets
associated with health have many similarities: high fiber, unsaturated fatty acids, and …

ABSTRACT A recent Perspective article described the “carbohydrate-insulin model (CIM)” of
obesity, asserting that it “better reflects knowledge on the biology of weight control” as …

Colorectal cancer (CRC) is among the most frequent forms of cancer, and new strategies for
its prevention and therapy are urgently needed. Here we identify a metabolite signalling …

According to a commonly held view, the obesity pandemic is caused by overconsumption of
modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary …

Nutrition has broad impacts on all physiological processes. However, how nutrition affects
human immunity remains largely unknown. Here we explored the impact of a dietary …

Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …

Purpose This paper aims to present an overview of the definitions of “plant-based and
“vegetarian diets” adopted by different organizations worldwide, proposing new standard …

Very-low-carbohydrate ketogenic diets have been long been used to reduce seizure
frequency and more recently have been promoted for a variety of health conditions …

The obesity pandemic continues unabated despite a persistent public health campaign to
decrease energy intake (“eat less”) and increase energy expenditure (“move more”). One …

The evolution of dietary guidelines from isolated nutrients to broader dietary pattern
recommendations results from growing knowledge of the synergy between nutrients and …