Cardiac surgery is associated with perioperative blood loss and a high risk of allogeneic
blood transfusion. Patient blood management (PBM) in cardiac surgery contributes to the …

Objective To compare patient outcomes of restrictive versus liberal blood transfusion
strategies in patients with cardiovascular disease not undergoing cardiac surgery. Design …

Background The effect of a restrictive versus liberal red-cell transfusion strategy on clinical
outcomes in patients undergoing cardiac surgery remains unclear. Methods In this …

Document Reviewers: Moritz WV Wyler von Ballmoos (USA), Mate Petricevic (Croatia), Arie
Pieter Kappetein (Netherlands), Miguel Sousa-Uva (Portugal), Georg Trummer (Germany) …

The Japanese Circulation Society (JCS) published the “Guidelines for elective percutaneous
coronary intervention [PCI] in patients with stable coronary disease” in 2000. In 2006 …

Sepsis is a major growing global burden and a major challenge to intensive care clinicians,
researchers, guideline committee members and policy makers, because of its high and …

Viscoelastic point-of-care tests are commonly used to provide prompt diagnosis of
coagulopathy and allow targeted treatments in bleeding patients. We updated existing meta …

Background: In an apparent paradox, morbidity and mortality are lower in obese patients
undergoing cardiac surgery, although the nature of this association is unclear. We sought to …

Anemia is common in elective surgery and is an independent risk factor for morbidity and
mortality. Historical management of anemia has focused on the use of allogeneic blood …

Aims To determine whether a restrictive strategy of red blood cell (RBC) transfusion at lower
haemoglobin concentrations is inferior to a liberal strategy of RBC transfusion at higher …