Autism spectrum disorder: Consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology

OD Howes, M Rogdaki, JL Findon… - Journal of …, 2018 - journals.sagepub.com
An expert review of the aetiology, assessment, and treatment of autism spectrum disorder,
and recommendations for diagnosis, management and service provision was coordinated …

Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease

E Lloyd-Evans, H Waller-Evans - Essays in Biochemistry, 2020 - portlandpress.com
Neurosteroids are steroid hormones synthesised de novo in the brain and peripheral
nervous tissues. In contrast to adrenal steroid hormones that act on intracellular nuclear …

Assessing sensory processing dysfunction in adults and adolescents with autism spectrum disorder: A scoping review

D DuBois, E Lymer, BE Gibson, P Desarkar, E Nalder - Brain sciences, 2017 - mdpi.com
Sensory reactivity is a diagnostic criterion for Autism Spectrum Disorder (ASD), and has
been associated with poorer functional outcomes, behavioral difficulties, and autism severity …

Immunological dysfunction in autism spectrum disorder: a potential target for therapy

J Marchezan, EGA Winkler dos Santos… - …, 2019 - karger.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with an
unknown etiology and currently few effective therapies. Immune system alterations have …

Toward an immune-mediated subtype of autism spectrum disorder

CJ McDougle, SM Landino, A Vahabzadeh, J O'Rourke… - Brain research, 2015 - Elsevier
A role for immunological involvement in autism spectrum disorder (ASD) has long been
hypothesized. This review includes four sections describing (1) evidence for a relationship …

Pharmacological management of behavioral disturbances in children and adolescents with autism spectrum disorders

M Lamy, CA Erickson - Current problems in pediatric and adolescent health …, 2018 - Elsevier
Autism spectrum disorder (ASD) is a heterogeneous neuropsychiatric condition that, based
on recent CDC estimates affects an estimated 1 in 59 American children. Behavioral …

Clinical trials in autism spectrum disorder: evidence, challenges and future directions

E Anagnostou - Current opinion in neurology, 2018 - journals.lww.com
Several compounds have evidence for the treatment of co-occurring symptoms in children
and youth with ASD, although pharmacological interventions for core symptoms are still …

Recent advances in the pharmacological management of behavioral disturbances associated with autism spectrum disorder in children and adolescents

M Lamy, EV Pedapati, KL Dominick, LK Wink… - Pediatric Drugs, 2020 - Springer
Autism spectrum disorder (ASD) is a heterogeneous neuropsychiatric condition affecting an
estimated one in 36 children. Youth with ASD may have severe behavioral disturbances …

Persistent angiogenesis in the autism brain: an immunocytochemical study of postmortem cortex, brainstem and cerebellum

EC Azmitia, ZT Saccomano, MF Alzoobaee… - Journal of autism and …, 2016 - Springer
In the current work, we conducted an immunocytochemical search for markers of ongoing
neurogenesis (eg nestin) in auditory cortex from postmortem sections of autism spectrum …

Beyond the brain: A multi-system inflammatory subtype of autism spectrum disorder

RP Thom, CJ Keary, ML Palumbo… - …, 2019 - Springer
An immune-mediated subtype of autism spectrum disorder (ASD) has long been
hypothesized. This article reviews evidence from family history studies of autoimmunity …