In the sanctity of pure drug discovery, objective reasoning can become clouded when
pursuing ideas that appear unorthodox, but are spot on physiologically. To put this into …

Zebrafish (Danio rerio) is a teleost fish widely accepted as a model organism for
neuroscientific studies. The adults show common basic vertebrate brain structures, together …

Background. Finding the associations between schizophrenia symptoms and the biomarkers
of inflammation, oxidative stress and the kynurenine pathway may lead to the …

Exposure to stressful life events during pregnancy exerts profound effects on
neurodevelopment and increases the risk for several neurodevelopmental disorders …

Depression is a psychiatric disorder characterized by various symptoms that can impact
one's quality of life. Vitamin D, a fat-soluble vitamin, is well-known for its role in bone health …

Depression is a serious global affective disorder and one of the most common neurological
diseases. Tanshinone IIA (TSA) is the mainly active constituent of Salvia miltiorrhiza and has …

Neurotrophins, such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF),
and neurotrophin 3 (NT-3), NT-4, and NT-5, are proteins involved in several important …

Objectives Depressive symptoms are commonly seen in schizophrenia. Increasing evidence
implicates that both SIRT1 and BDNF closely related to the development of depression. So …

Background Schizophrenia is associated with patterns of aberrant neurobiological circuitry.
The disease complexity is mirrored by multiple biological interactions known to contribute to …

Recent findings have led to the discovery of many signaling pathways that link nuclear
receptors with human conditions, including mental decline and neurodegenerative …