[HTML][HTML] Function of lipid droplet-organelle interactions in lipid homeostasis

AD Barbosa, S Siniossoglou - … et Biophysica Acta (BBA)-Molecular Cell …, 2017 - Elsevier
Storage of non-polar lipids in ubiquitous eukaryotic organelles, lipid droplets (LDs), prevents
the toxic consequences of unesterified fatty acids and provides a lipid reservoir that can be …

Unearthing the alteration in plant volatiles induced by mycorrhizal fungi: A shield against plant pathogens

AK Sarkar, S Sadhukhan - Physiologia Plantarum, 2023 - Wiley Online Library
Plants produce a large range of structurally varied low molecular weight secondary
metabolites, which evaporate, known as volatile organic compounds (VOCs). Several of …

Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis

T Shpilka, E Welter, N Borovsky, N Amar, M Mari… - The EMBO …, 2015 - embopress.org
Autophagy is a major catabolic process responsible for the delivery of proteins and
organelles to the lysosome/vacuole for degradation. Malfunction of this pathway has been …

Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation

NO Speer, RJ Braun, EG Reynolds, A Brudnicka… - Journal of Cell …, 2023 - rupress.org
Cells store lipids in the form of triglyceride (TG) and sterol ester (SE) in lipid droplets (LDs).
Distinct pools of LDs exist, but a pervasive question is how proteins localize to and convey …

[HTML][HTML] ORP5 localizes to ER–lipid droplet contacts and regulates the level of PI (4) P on lipid droplets

X Du, L Zhou, YC Aw, HY Mak, Y Xu, J Rae… - Journal of Cell …, 2020 - rupress.org
Lipid droplets (LDs) are evolutionarily conserved organelles that play important roles in
cellular metabolism. Each LD is enclosed by a monolayer of phospholipids, distinct from …

Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation

M Eisenberg-Bord, M Mari, U Weill… - Journal of Cell …, 2018 - rupress.org
Functional heterogeneity within the lipid droplet (LD) pool of a single cell has been
observed, yet the underlying mechanisms remain enigmatic. Here, we report on …

Pleiotropic roles of Ras GTPases in the nematode-trapping fungus Arthrobotrys oligospora identified through multi-omics analyses

L Yang, X Li, M Xie, N Bai, J Yang, K Jiang, KQ Zhang… - IScience, 2021 - cell.com
The nematode-trapping fungi are ideal agents for controlling pathogenic nematodes.
Arthrobotrys oligospora is a representative species of the same, producing traps for …

Lipid droplets are essential for efficient clearance of cytosolic inclusion bodies

O Moldavski, T Amen, S Levin-Zaidman, M Eisenstein… - Developmental cell, 2015 - cell.com
Exposing cells to folding stress causes a subset of their proteins to misfold and accumulate
in inclusion bodies (IBs). IB formation and clearance are both active processes, but little is …

Regulation of lipid droplets by metabolically controlled Ldo isoforms

V Teixeira, L Johnsen, F Martínez-Montañés… - Journal of Cell …, 2018 - rupress.org
Storage and consumption of neutral lipids in lipid droplets (LDs) are essential for energy
homeostasis and tightly coupled to cellular metabolism. However, how metabolic cues are …

Born this way–Biogenesis of lipid droplets from specialized ER subdomains

NT Nettebrock, M Bohnert - Biochimica et Biophysica Acta (BBA)-Molecular …, 2020 - Elsevier
Both the endoplasmic reticulum (ER) and lipid droplets (LDs) are key players in lipid
handling. In addition to this functional connection, the two organelles are also tightly linked …