Anticancer agents are critical for the cancer treatment, but side effects and the drug
resistance associated with the currently used anticancer agents create an urgent need to …

Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access to
the molecular diversity and unique functions of complex natural products up to now. It …

Cancer is one of the greatest challenges of the modern medicine. Although much effort has
been made in the development of novel cancer therapeutics, it still remains one of the most …

Natural products play a key role in the history of human drug discovery, and especially for
the anticancer agents. Copper (I)-catalyzed alkyne-azide [3+ 2] cycloaddition (CuAAC) …

Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex
hormone that not only promotes the development of female secondary sexual …

The first review article on steroid dimers by Li and Dias in 1997, followed by the second
review and a book on steroid dimers by Nahar and Sarker in 2007 and 2012, respectively …

Leukemia, a hematological malignancy originating from the bone marrow, is the principal
cancer of childhood. In recent decades, improved remission rates and survival of patients …

Materials and Methods: The cytotoxicity of the newly synthesized compounds was assessed
against different human cancer cell lines including MCF-7, A2780, MCF-7/MX, A2780/RCIS …

Nanosecond pulsed electric field offers novel opportunities in bionanotechnology and
biomedicine enabling ultrafast physical control of membrane, and protein‐based processes …

The clinical application of 2-methoxyestradiol (2ME) in cancer therapy has been limited by
its low solubility and rapid metabolism. Derivatives of 2ME have been synthesised to …