Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistanis and Bangladeshis

QQ Huang, N Sallah, D Dunca, B Trivedi, KA Hunt… - medRxiv, 2021 - medrxiv.org
Abstract Background Individuals with South Asian ancestry have higher risk of heart disease
than other groups in Western countries; however, most genetic research has focused on …

Identification of functional genetic variants associated with alcohol dependence and related phenotypes using a high‐throughput assay

KS Thapa, AB Chen, D Lai, X Xuei… - Alcoholism: Clinical …, 2020 - Wiley Online Library
Background Genome‐wide association studies (GWAS) of alcohol dependence (AD) and
related phenotypes have identified multiple loci, but the functional variants underlying the …

[HTML][HTML] Predicting alcohol-related memory problems in older adults: A machine learning study with multi-domain features

C Kamarajan, AK Pandey, DB Chorlian, JL Meyers… - Behavioral …, 2023 - mdpi.com
Memory problems are common among older adults with a history of alcohol use disorder
(AUD). Employing a machine learning framework, the current study investigates the use of …

A Genome-Wide Association Study Reveals New Genes in a Molecular Network Associated With Alcohol Dependence and Related Clinical Measures

A Levchenko, S Malov, A Antonik, A Protsvetkina… - 2022 - preprints.org
At least 50% of factors predisposing to alcohol dependence (AD) are genetic and women
affected with this disorder present with more psychiatric comorbidities, probably indicating …

[PDF][PDF] Interactions between genome-wide polygenic scores for alcohol consumption and a broad spectrum of environmental factors

R Kandaswamy, S Cave, A Allegrini, R Plomin… - osf.io
Adolescence is a critical period for experimenting with alcohol, which becomes legally
accessible for young people between the ages of 16 and 18 years in the United Kingdom. In …