The complex role of MEG3: An emerging long non-coding RNA in breast cancer

MS Hussain, AA Majami, H Ali, G Gupta… - … -Research and Practice, 2023 - Elsevier
MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …

The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

X Meng, QY Lou, WY Yang, YR Wang… - Cancer …, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis

Y Liang, X Song, Y Li, B Chen, W Zhao, L Wang… - Molecular cancer, 2020 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play crucial roles in tumor
progression and are aberrantly expressed in various cancers. However, the functional roles …

[HTML][HTML] Maternally expressed gene 3 (MEG3): A tumor suppressor long non coding RNA

S Ghafouri-Fard, M Taheri - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract Maternally expressed gene 3 (MEG3) is a long non-coding RNA (lncRNA) located
on chromosome 14q32. 3. Direct sequencing experiments have shown monoallelic …

Noncoding RNAs in age-related cardiovascular diseases

A Jusic, PB Thomas, SB Wettinger, S Dogan… - Ageing Research …, 2022 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …

[HTML][HTML] Tight junctions and their regulation by non-coding RNAs

X Zhao, H Zeng, L Lei, X Tong, L Yang… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Tight junction (TJ) is a “zippering up” junction structure located at the uppermost portion of
adjacent epithelial/endothelial cells in organs and tissues. TJs maintain the relative stability …

[HTML][HTML] Emerging role of long non-coding RNAs in endothelial dysfunction and their molecular mechanisms

R Jayasuriya, K Ganesan, B Xu… - Biomedicine & …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) are the novel class of transcripts involved in
transcriptional, post-transcriptional, translational, and post-translational regulation of …

Vascular endothelial senescence: pathobiological insights, emerging long noncoding RNA targets, challenges and therapeutic opportunities

X Sun, MW Feinberg - Frontiers in Physiology, 2021 - frontiersin.org
Cellular senescence is a stable form of cell cycle arrest in response to various stressors.
While it serves as an endogenous pro-resolving mechanism, detrimental effects ensue when …

[PDF][PDF] Deregulated expression of the imprinted DLK1-DIO3 region in glioblastoma stemlike cells: tumor suppressor role of lncRNA MEG3

M Buccarelli, V Lulli, A Giuliani, M Signore… - Neuro …, 2020 - academic.oup.com
Background Glioblastoma (GBM) stemlike cells (GSCs) are thought to be responsible for the
maintenance and aggressiveness of GBM, the most common primary brain tumor in adults …

Aptamer-Functionalized Dendrimer Delivery of Plasmid-Encoding lncRNA MEG3 Enhances Gene Therapy in Castration-Resistant Prostate Cancer

Z Tai, J Ma, J Ding, H Pan, R Chai, C Zhu… - International journal …, 2020 - Taylor & Francis
Purpose The clinical management of patients with castration-resistant prostate cancer
(CRPC) is difficult. However, novel treatment methods are gradually being introduced …