The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …

Rationale Love has long been referred to as an addiction in literature and poetry. Scientists
have often made comparisons between social attachment processes and drug addiction …

Drug use typically occurs within a social context, and social factors play an important role in
the initiation, maintenance and recovery from addictions. There is now accumulating …

Recent research shows that the effects of oxytocin are more diverse than initially thought
and that in some cases oxytocin can directly influence the response to drugs and alcohol …

Development of new treatments for drug addiction will depend on high-throughput screening
in animal models. However, an addiction biomarker fit for rapid testing, and useful in both …

The mesolimbic dopamine (DA) circuitry determines which behaviors are positively
reinforcing and therefore should be encoded in the memory to become a part of the …

Oxytocin administration has been reported to decrease consumption, withdrawal, and drug-
seeking associated with several drugs of abuse and thus represents a promising …

Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and
supraoptic nuclei within the hypothalamus. Like other neuropeptides, oxy can modulate a …

Alcohol dependence is a chronically relapsing disorder characterized by compulsive drug-
seeking and drug-taking, loss of control in limiting intake, and the emergence of a …