Insulitis in human type 1 diabetes: lessons from an enigmatic lesion

NG Morgan - European Journal of Endocrinology, 2024 - academic.oup.com
Type 1 diabetes is caused by a deficiency of insulin secretion which has been considered
traditionally as the outcome of a precipitous decline in the viability of β-cells in the islets of …

Hydrogel-encapsulated pancreatic islet cells as a promising strategy for diabetic cell therapy

Z Huan, J Li, Z Luo, Y Yu, L Li - Research, 2024 - spj.science.org
Islet transplantation has now become a promising treatment for insulin-deficient diabetes
mellitus. Compared to traditional diabetes treatments, cell therapy can restore endogenous …

Local dialogues between the endocrine and exocrine cells in the pancreas

M Slak Rupnik, M Hara - Diabetes, 2024 - Am Diabetes Assoc
For many years, it has been taught in medical textbooks that the endocrine and exocrine
parts of the pancreas have separate blood supplies that do not mix. Therefore, they have …

Diabetes as a Pancreatic Microvascular Disease—A Pericytic Perspective

L Mateus Gonçalves… - … of Histochemistry & …, 2024 - journals.sagepub.com
Diabetes is not only an endocrine but also a vascular disease. Vascular defects are usually
seen as consequence of diabetes. However, at the level of the pancreatic islet, vascular …

Unraveling the interplay: exploring signaling pathways in pancreatic cancer in the context of pancreatic embryogenesis

S Swain, RK Narayan, PR Mishra - Frontiers in Cell and …, 2024 - frontiersin.org
Pancreatic cancer continues to be a deadly disease because of its delayed diagnosis and
aggressive tumor biology. Oncogenes and risk factors are being reported to influence the …

[HTML][HTML] Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis

Y Chen, X Yin, R Xu, R Ruze, J Song, C Yin, C Hu… - Gastroenterology, 2024 - Elsevier
Background & Aims The pancreas is composed of endocrine and exocrine parts, and its
interlacing structure indicates potential interaction between endocrine and exocrine cells …