[HTML][HTML] Gram-positive bacterial cell envelopes: The impact on the activity of antimicrobial peptides
N Malanovic, K Lohner - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
A number of cationic antimicrobial peptides, effectors of innate immunity, are supposed to
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …
act at the cytoplasmic membrane leading to permeabilization and eventually membrane …
Antimicrobial peptides targeting gram-positive bacteria
N Malanovic, K Lohner - Pharmaceuticals, 2016 - mdpi.com
Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …
The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms
A de Breij, M Riool, RA Cordfunke… - Science translational …, 2018 - science.org
Development of novel antimicrobial agents is a top priority in the fight against multidrug-
resistant (MDR) and persistent bacteria. We developed a panel of synthetic antimicrobial …
resistant (MDR) and persistent bacteria. We developed a panel of synthetic antimicrobial …
[HTML][HTML] The human cathelicidin LL-37—A pore-forming antibacterial peptide and host-cell modulator
The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …
[HTML][HTML] Membrane-active host defense peptides–challenges and perspectives for the development of novel anticancer drugs
S Riedl, D Zweytick, K Lohner - Chemistry and physics of lipids, 2011 - Elsevier
Although much progress has been achieved in the development of cancer therapies in
recent decades, problems continue to arise particularly with respect to chemotherapy due to …
recent decades, problems continue to arise particularly with respect to chemotherapy due to …
Design of antimicrobial peptides: progress made with human cathelicidin LL-37
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …
health due to the rapid replication of invading microbes and the delayed action of the …
Multifunctional host defense peptides: intracellular‐targeting antimicrobial peptides
P Nicolas - The FEBS journal, 2009 - Wiley Online Library
There is widespread acceptance that cationic antimicrobial peptides, apart from their
membrane‐permeabilizing/disrupting properties, also operate through interactions with …
membrane‐permeabilizing/disrupting properties, also operate through interactions with …
[HTML][HTML] High-quality 3D structures shine light on antibacterial, anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments
Host defense antimicrobial peptides are key components of human innate immunity that
plays an indispensible role in human health. While there are multiple copies of cathelicidin …
plays an indispensible role in human health. While there are multiple copies of cathelicidin …
The revitalization of antimicrobial peptides in the resistance era
Y Liu, J Shi, Z Tong, Y Jia, B Yang, Z Wang - Pharmacological Research, 2021 - Elsevier
The antibiotic resistance crisis is becoming incredibly thorny due to the indiscriminate
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …
employment of antibiotics in agriculture and aquaculture, such as growth promoters, and the …
Antimicrobial peptides increase line tension in raft-forming lipid membranes
VR Koynarev, KKA Borgos, J Kohlbrecher… - Journal of the …, 2024 - ACS Publications
The formation of phase separated membrane domains is believed to be essential for the
function of the cell. The precise composition and physical properties of lipid bilayer domains …
function of the cell. The precise composition and physical properties of lipid bilayer domains …