Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

Hematopoietic stem cells (HSCs) are regarded as one of essential cell sources for treating
regenerative diseases. Among many stem cells, the feasibility of using adult-derived …

Microvesicles (MVs) are released by almost all cells in resting and activated conditions. First
described several years ago, it is only recently that their mechanisms of action are being …

Acute-on-chronic liver failure (ACLF) is a distinct syndrome of liver failure in a patient with
chronic liver disease presenting with jaundice, coagulopathy and ascites and/or hepatic …

Liver transplantation represents the standard treatment for people with an end-stage liver
disease and some liver-based metabolic disorders; however, shortage of liver donor tissues …

Background As morbidity and mortality from liver disease continues to rise, new strategies
are necessary. Liver transplantation is not only an expensive resource committing the …

End-stage liver disease (ESLD) is characterized by the deterioration of liver function and a
subsequent high mortality rate. Studies have investigated the use of adult stem cells to treat …

The present study assessed the effects of intraportal infusions of autologous bone marrow-
derived mononuclear cells (MNCs) and/or CD133+ cells on liver function in patients with …

Background aims Macrophages have complex roles in the liver. The aim of this study was to
compare profiles of human monocyte-derived macrophages between controls and cirrhotic …

End-stage disease due to liver cirrhosis is an important cause of death worldwide. Cirrhosis
results from progressive, extensive fibrosis and impaired hepatocyte regeneration. The only …