The treatment of inflammatory bowel disease (IBD) has been revolutionised over the past
decade by the increasing use of immunomodulators, mainly azathioprine (AZA)/6 …

Test accuracy of interferon-γ release assays (IGRAs) for diagnosing TB differs when using
older or precommercial tools and inconsistent diagnostic criteria. This metaanalysis critically …

In 2005, CDC published guidelines for using the QuantiFERON-TB Gold test (QFT-
G)(Cellestis Limited, Carnegie, Victoria, Australia)(CDC. Guidelines for using the …

Background. The diagnostic value of interferon-γ release assays (IGRAs) for active
tuberculosis in low-and middle-income countries is unclear. Methods. We searched multiple …

ABSTRACT QuantiFERON-TB Gold Plus (QFT-Plus) is the latest generation of interferon
gamma release assays (IGRAs) to receive approval from the US FDA, replacing its …

Despite the identification of Mycobacterium tuberculosis as the cause of tuberculosis (TB)
more than a century ago, diagnosing TB in resource-poor countries remains a challenge …

Background Despite the widespread use of interferon-γ release assays (IGRAs), their role in
diagnosing tuberculosis and targeting preventive therapy in HIV-infected patients remains …

The last decade has witnessed significant advances in mycobacterial genomics and cellular
research which have resulted in the development of two new blood tests, the enzyme-linked …

Tuberculosis ranges among the leading causes of morbidity and mortality worldwide. A
diagnostic approach to a patient with possible tuberculosis includes a detailed medical …

The current state-of-the-art tests for infection with Mycobacterium tuberculosis–the IFN-γ
release assays–rely on accurate measurement of the cytokine IFN-γ. Many other potential …