The Matching and Proportional Laws are heuristic control policies that have found
widespread use in cybernetic models of biological systems. Within this context, the laws …

Industrial fermentations typically use media that are balanced with multiple substitutable
substrates including complex carbon and nitrogen source. Yet, much of the modeling effort …

Despite many environmental advantages of using alcohol as a fuel, there are still serious
questions about its economical feasibility when compared with oil‐based fuels. The …

Mixed-substrate microbial growth is of fundamental interest in microbiology and
bioengineering. Several mathematical models have been developed to account for the …

Denitrification is a multistage reduction process converting nitrate ultimately to nitrogen gas,
carried out mostly by facultative bacteria. Modeling of the denitrification process is …

We have shown that Pseudomonas denitrificans undergo a diauxie when switching from
dissolved oxygen to nitrate as terminal electron acceptor. The length of time under aeration …

A simple model has been formulated to simulate diauxic growth of denitrifying bacteria. It is
capable of fitting the experimental results of batch growth experiments with Pseudomonas …

The germination of spores is the initial stage of fermentation processes, in which filamentous
fungi are involved. The qualitative and quantitative description of this process is very …

The simultaneous saccharification and fermentation (SSF) process consists of concurrent
enzymatic saccharification and fermentation. In the present cybernetic model, the …

In this chapter, principles of modeling of biotechnical processes will be introduced. The
focus is set onto models of the biological system within the entire bioprocess, as its most …