Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

The respiratory tree maintains sterilizing immunity against human fungal pathogens.
Humans inhale ubiquitous filamentous molds and geographically restricted dimorphic fungal …

Summary The interleukin (IL)-17 family, consisting of six members, promotes host defense
but can in some context promote the development of autoimmune disease. Here, we …

IgE, the key molecule in atopy has been shown to bind two receptors, FcεRI, the high‐affinity
receptor, and FcεRII (CD23), binding IgE with lower affinity. Whereas cross‐linking of IgE on …

Fungi are opportunistic pathogens that infect immunocompromised patients and are
responsible for an estimated 1.5 million deaths every year. The antifungal innate immune …

Phagocytosis is a cellular process maintaining tissue balance and plays an essential role in
initiating the innate immune response. The process of phagocytosis was triggered by the …

During the course of fungal infection, pathogen recognition by the innate immune system is
critical to initiate efficient protective immune responses. The primary event that triggers …

C‐type lectin receptors (CLRs) constitute a category of innate immune receptors that play an
essential role in the antifungal immune response. For over two decades, scientists have …

Invasive fungal infections are life-threatening, and neutrophils are vital cells of the innate
immune system that defend against them. The role of LTA4H-LTB4-BLT1 axis in regulation …