The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

Background: A terrible pandemic, Covid-19, has captivated scientists to investigate if SARS-
CoV-2 virus infects the central nervous system (CNS). A crucial question is if acute …

Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden
for patients, families, and society worldwide. As part of the Curing Coma Campaign, the …

Importance Given its selective action on the ω1 subtype of the γ-aminobutyric acid A
receptor, zolpidem tartrate presents a potential treatment mechanism for other neurologic …

Major advances have been made over the past few decades in identifying and managing
disorders of consciousness (DOC) in patients with acquired brain injury (ABI), bringing the …

In the human electroencephalogram (EEG), oscillatory power co-exist with non-oscillatory,
aperiodic activity. Although EEG analysis has traditionally focused exclusively on oscillatory …

This is a retrospective study to investigate the results of using zolpidem and lorazepam in
persons with disorders of consciousness (DoC) and to provide practical information for …

Coma is a medical and socioeconomic emergency. Although underfunded, research on
coma and disorders of consciousness has made impressive progress. Lesion-network …

Key autonomic functions are in continuous development during adolescence which can be
assessed using the heart rate variability (HRV). However, the influence of different …

We compare and discuss three cases including: a clearly brain-dead patient, a vegetative
state/unresponsive wakefulness syndrome (VS/UWS) patient and a patient diagnosed as …