The role of ABC transporters in ovarian cancer progression and chemoresistance
Over 80% of ovarian cancer patients develop chemoresistance which results in a lethal
course of the disease. A well-established cause of chemoresistance involves the family of …
course of the disease. A well-established cause of chemoresistance involves the family of …
[HTML][HTML] Chemotherapy resistance mechanisms in advanced skin cancer
Melanoma is a most dangerous and deadly type of skin cancer, and considered intrinsically
resistant to both radiotherapy and chemotherapy. It has become a major public health …
resistant to both radiotherapy and chemotherapy. It has become a major public health …
Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1Bhigh cells
Despite success with BRAFV600E inhibitors, therapeutic responses in patients with
metastatic melanoma are short-lived because of the acquisition of drug resistance. We …
metastatic melanoma are short-lived because of the acquisition of drug resistance. We …
Exploitation of Long-Lived 3IL Excited States for Metal–Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model
Members of a family of Ru (II)-appended pyrenylethynylene dyads were synthesized,
characterized according to their photophysical and photobiological properties, and …
characterized according to their photophysical and photobiological properties, and …
Transcriptome analysis and molecular signature of human retinal pigment epithelium
NV Strunnikova, A Maminishkis, JJ Barb… - Human molecular …, 2010 - academic.oup.com
Retinal pigment epithelium (RPE) is a polarized cell layer critical for photoreceptor function
and survival. The unique physiology and relationship to the photoreceptors make the RPE a …
and survival. The unique physiology and relationship to the photoreceptors make the RPE a …
[HTML][HTML] Failed apoptosis enhances melanoma cancer cell aggressiveness
K Berthenet, CC Ferrer, D Fanfone, N Popgeorgiev… - Cell Reports, 2020 - cell.com
Triggering apoptosis remains an efficient strategy to treat cancer. However, apoptosis is no
longer a final destination since cancer cells can undergo partial apoptosis without dying …
longer a final destination since cancer cells can undergo partial apoptosis without dying …
Revisiting the ABCs of multidrug resistance in cancer chemotherapy
The adenosine triphosphate binding cassette (ABC) transporters are one of the largest
transmembrane gene families in humans. The ABC transporters are present in a number of …
transmembrane gene families in humans. The ABC transporters are present in a number of …
[HTML][HTML] miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1
MicroRNAs (miRNAs) are short noncoding RNAs that play crucial roles in tumorigenesis and
tumor progression. Melanoma is the most aggressive skin cancer that is resistant or rapidly …
tumor progression. Melanoma is the most aggressive skin cancer that is resistant or rapidly …
[PDF][PDF] Photodynamic therapy in melanoma—an update
Melanoma, a cancer that arises from melanocytes is one of the most unresponsive cancers
to known therapies. Several studies showed encouraging results of the efficacy of …
to known therapies. Several studies showed encouraging results of the efficacy of …
The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
JJ Hsiao, DE Fisher - Archives of biochemistry and biophysics, 2014 - Elsevier
MITF and pigmentation play important roles in both normal melanocyte and transformed
melanoma cell biology. MITF is regulated by many pathways and it also regulates many …
melanoma cell biology. MITF is regulated by many pathways and it also regulates many …