Nanopore single-molecule analysis of biomarkers: Providing possible clues to disease diagnosis

X Chen, S Zhou, Y Wang, L Zheng, S Guan… - TrAC Trends in …, 2023 - Elsevier
Biomarker detection has attracted increasing interest in recent years due to the minimally or
non-invasive sampling process. Single entity analysis of biomarkers is expected to provide …

Protein nanopore-based sensors for public health analyte detection

Y Zhang, C Hu, R Liu, S He, J Yang, W Yao… - Journal of Materials …, 2024 - pubs.rsc.org
High-throughput and label-free protein nanopore-based sensors are extensively used in
DNA sequencing, single-protein analysis, molecular sensing and chemical catalysis with …

Nanopore discrimination and sensitive plasma detection of multiple natriuretic peptides: The representative biomarker of human heart failure

S Zhang, Y Wang, D Song, S Guan, D Zhou… - Biosensors and …, 2023 - Elsevier
Natriuretic peptides can relieve cardiovascular stress and closely related to heart failure.
Besides, these peptides also have preferable interactions of binding to cellular protein …

Improving the performance of selective solid-state nanopore sensing using a polyhistidine-tagged monovalent streptavidin

S Abu Jalboush, ID Wadsworth, K Sethi… - ACS …, 2024 - ACS Publications
Solid-state (SS-) nanopore sensing has gained tremendous attention in recent years, but it
has been constrained by its intrinsic lack of selectivity. To address this, we previously …

Label-free high-precise nanopore detection of endopeptidase activity of anthrax lethal factor regulated by diverse conditions

M Li, S Chen, Y Wang, S Zhang, D Song, R Tian… - Biosensors and …, 2023 - Elsevier
Endopeptidase activity of anthrax lethal factor (aLF) prevents the destroy of anthracis spore
intracellularly by host macrophages, meanwhile disables the signaling pathways …

Single‐Molecule Measurement of Carbonic Anhydrase in Cation Coordinated Environment Using MspA Nanopore

D Song, Y Wang, S Zhang, L Zhao… - Chinese Journal of …, 2023 - Wiley Online Library
Comprehensive Summary Carbonic anhydrase accounts for catalytic reaction of CO2/HCO3–
transformation, thus resulting in neutralization and acidification of the cellular environment …

[HTML][HTML] Nanopore-based glycan sequencing: state of the art and future prospects

G Yao, W Ke, B Xia, Z Gao - Chemical Science, 2024 - ncbi.nlm.nih.gov
Sequencing of biomacromolecules is a crucial cornerstone in life sciences. Glycans, one of
the fundamental biomolecules, derive their physiological and pathological functions from …

Nanopore-based glycan sequencing: state of the art and future perspective

Z Gao, G Yao, W Ke, BB Xia - Chemical Science, 2024 - pubs.rsc.org
Sequencing of biomacromolecules is a crucial cornerstone in the life sciences. Glycans, one
of the fundamental biomolecules, derive their physiological and pathological functions from …

Molecular sandwich-based DNAzyme catalytic reaction towards transducing efficient nanopore electrical detection of antigen proteins

L Wang, S Zhou, Y Wang, Y Wang, J Li, X Chen… - Faraday …, 2025 - pubs.rsc.org
Despite significant advances in nanopore nucleic acid sequencing and sensing, protein
detection remains challenging due to the inherent complexity of protein molecular properties …

[PDF][PDF] CJC

D Song, Y Wang, S Zhang, L Zhao, L Gong, L Liang… - researchgate.net
Carbonic anhydrase accounts for catalytic reaction of CO2/HCO3-transformation, thus
resulting in neutralization and acidification of the cellular environment, thereby favoring …