Colorectal cancer (CRC) involving a malignant tumour remains one of the greatest
contributing causes of fatal mortality and has become the third globally ranked malignancy …

Photodynamic therapy (PDT), a promising treatment option for cancer, involves the
activation of a photosensitizer (PS) by local irradiation with visible light. Excitation of the PS …

Simple Summary Cancer remains one of the leading causes of death worldwide. The
advancements in 3D tumour models provide in vitro test-beds to study cancer growth …

Purpose Previous analyses of the tumor microenvironment (TME) have resulted in a concept
that tumor progression may depend on interactions between cancer cells and its …

Tumor microenvironment (TME) is a dynamic ecosystem where fibroblasts are recruited in
order to provide a niche to support growth and, in some extent, to promote therapeutic …

The study of cellular interactions in the tumor microenvironment has become one of the main
areas of research in the fight against cancer. Tumor-associated macrophages (TAMs) …

Cancer is a physiologically and molecularly heterogeneous disease in which therapeutic
contingency majorly depends on the developmental stage and intrinsic-genotypic profile …

Photodynamic Therapy (PDT) has recently gain attention as alternative treatment of Central
Nervous System (CNS) cancer diseases, due to the demonstration of successfully …

The development of effective cancer therapies is required to improve outcomes in colorectal
cancer (CRC) treatment. Photodynamic therapy (PDT) has been proposed as more …

The development of biomimetic, human tissue models is recognized as being an important
step for transitioning in vitro research findings to the native in vivo response. Oftentimes, 2D …