Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively
associated with cardiovascular and neurodegenerative diseases. However, findings from …

Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …

Aging is associated with an increased risk of cardiovascular disease and death. Here we
show that oral supplementation of the natural polyamine spermidine extends the lifespan of …

Decreased cognitive performance is a hallmark of brain aging, but the underlying
mechanisms and potential therapeutic avenues remain poorly understood. Recent studies …

Background: Blood lipids are established risk factors for myocardial infarction (MI), but
uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating …

Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Altered metabolism of lipids is currently considered a hallmark characteristic of many
malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites …

Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

Background Coronary artery disease (CAD) is associated with gut microbiota alterations in
different populations. Gut microbe-derived metabolites have been proposed as markers of …

Background—High-throughput profiling of circulating metabolites may improve
cardiovascular risk prediction over established risk factors. Methods and Results—We …