An updated review of lysophosphatidylcholine metabolism in human diseases
SH Law, ML Chan, GK Marathe, F Parveen… - International journal of …, 2019 - mdpi.com
Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively
associated with cardiovascular and neurodegenerative diseases. However, findings from …
associated with cardiovascular and neurodegenerative diseases. However, findings from …
Systems biology in cardiovascular disease: a multiomics approach
Omics techniques generate large, multidimensional data that are amenable to analysis by
new informatics approaches alongside conventional statistical methods. Systems theories …
new informatics approaches alongside conventional statistical methods. Systems theories …
Cardioprotection and lifespan extension by the natural polyamine spermidine
T Eisenberg, M Abdellatif, S Schroeder, U Primessnig… - Nature medicine, 2016 - nature.com
Aging is associated with an increased risk of cardiovascular disease and death. Here we
show that oral supplementation of the natural polyamine spermidine extends the lifespan of …
show that oral supplementation of the natural polyamine spermidine extends the lifespan of …
[HTML][HTML] Dietary spermidine improves cognitive function
Decreased cognitive performance is a hallmark of brain aging, but the underlying
mechanisms and potential therapeutic avenues remain poorly understood. Recent studies …
mechanisms and potential therapeutic avenues remain poorly understood. Recent studies …
Lipids, lipoproteins, and metabolites and risk of myocardial infarction and stroke
MV Holmes, IY Millwood, C Kartsonaki, MR Hill… - Journal of The American …, 2018 - jacc.org
Background: Blood lipids are established risk factors for myocardial infarction (MI), but
uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating …
uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating …
Inflammatory processes in cardiovascular disease: a route to targeted therapies
Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …
Changes in lipids composition and metabolism in colorectal cancer: a review
A Pakiet, J Kobiela, P Stepnowski, T Sledzinski… - Lipids in health and …, 2019 - Springer
Altered metabolism of lipids is currently considered a hallmark characteristic of many
malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites …
malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites …
Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …
practice. Progress in high-throughput technologies has provided new opportunities to …
Alterations in the gut microbiome and metabolism with coronary artery disease severity
H Liu, X Chen, X Hu, H Niu, R Tian, H Wang, H Pang… - Microbiome, 2019 - Springer
Background Coronary artery disease (CAD) is associated with gut microbiota alterations in
different populations. Gut microbe-derived metabolites have been proposed as markers of …
different populations. Gut microbe-derived metabolites have been proposed as markers of …
Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts
P Würtz, AS Havulinna, P Soininen, T Tynkkynen… - Circulation, 2015 - Am Heart Assoc
Background—High-throughput profiling of circulating metabolites may improve
cardiovascular risk prediction over established risk factors. Methods and Results—We …
cardiovascular risk prediction over established risk factors. Methods and Results—We …