Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Bone defects requiring grafts to promote healing are frequently occurring and costly
problems in health care. Chitosan, a biodegradable, naturally occurring polymer, has drawn …

Hydroxyapatite (HA) is an essential element required for bone regeneration. Different forms
of HA have been used for a long time. The essence of bone regeneration always revolves …

This review focuses on calcium phosphate-based bone substitute materials that are used (or
can be used) for teeth or bone replacement, bone repair, augmentation, or regeneration …

Biomaterials can be endowed with biologically instructive properties by changing basic
parameters such as elasticity and surface texture. However, translation from in vitro proof of …

In the past thirty years, a number of biomaterials have shown the ability to induce bone
formation when implanted at heterotopic sites, an ability known as osteoinduction. Such …

Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process
by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage …

Orthopaedic trauma surgery requires the regular use of bone grafts to help provide timely
healing of musculoskeletal injuries. The iliac crest autologous graft remains the gold …

Various types of grafts have been traditionally used to restore damaged bones. In the late
1960s, a strong interest was raised in studying ceramics as potential bone grafts due to their …