[HTML][HTML] Computational fluid dynamics modelling in cardiovascular medicine

PD Morris, A Narracott, H von Tengg-Kobligk… - Heart, 2016 - heart.bmj.com
This paper reviews the methods, benefits and challenges associated with the adoption and
translation of computational fluid dynamics (CFD) modelling within cardiovascular medicine …

Cardiovascular models for personalised medicine: Where now and where next?

DR Hose, PV Lawford, W Huberts, LR Hellevik… - Medical engineering & …, 2019 - Elsevier
The aim of this position paper is to provide a brief overview of the current status of
cardiovascular modelling and of the processes required and some of the challenges to be …

In-silico trial of intracranial flow diverters replicates and expands insights from conventional clinical trials

A Sarrami-Foroushani, T Lassila, M MacRaild… - Nature …, 2021 - nature.com
The cost of clinical trials is ever-increasing. In-silico trials rely on virtual populations and
interventions simulated using patient-specific models and may offer a solution to lower these …

Accuracy vs. computational time: translating aortic simulations to the clinic

AG Brown, Y Shi, A Marzo, C Staicu, I Valverde… - Journal of …, 2012 - Elsevier
State of the art simulations of aortic haemodynamics feature full fluid-structure interaction
(FSI) and coupled 0D boundary conditions. Such analyses require not only significant …

Wall shear stress at the initiation site of cerebral aneurysms

AJ Geers, HG Morales, I Larrabide, C Butakoff… - … and modeling in …, 2017 - Springer
Hemodynamics are believed to play an important role in the initiation of cerebral aneurysms.
In particular, studies have focused on wall shear stress (WSS), which is a key regulator of …

Intra-aneurysmal pressure and flow changes induced by flow diverters: relation to aneurysm size and shape

I Larrabide, ML Aguilar, HG Morales… - American Journal …, 2013 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Effects of blood flow modification by flow diverters are
observed to lead often to aneurysm thrombosis and reverse remodeling. For this process, to …

Thrombosis in cerebral aneurysms and the computational modeling thereof: a review

MN Ngoepe, AF Frangi, JV Byrne, Y Ventikos - Frontiers in physiology, 2018 - frontiersin.org
Thrombosis is a condition closely related to cerebral aneurysms and controlled thrombosis
is the main purpose of endovascular embolization treatment. The mechanisms governing …

Transitional flow in aneurysms and the computation of haemodynamic parameters

C Poelma, PN Watton… - Journal of The Royal …, 2015 - royalsocietypublishing.org
Haemodynamic forces appear to play an influential role in the evolution of aneurysms. This
has led to numerous studies, usually based on computational fluid dynamics. Their focus is …

[PDF][PDF] Mechanobiology of the arterial wall

AM Robertson, PN Watton - Transport in biological Media, 2013 - Citeseer
The proper functioning of the arterial wall is vital to the health of the individual, as evidenced
by the numerous debilitating medical problems which can arise when the wall falls prey to …

Approximating hemodynamics of cerebral aneurysms with steady flow simulations

AJ Geers, I Larrabide, HG Morales, AF Frangi - Journal of biomechanics, 2014 - Elsevier
Computational fluid dynamics (CFD) simulations can be employed to gain a better
understanding of hemodynamics in cerebral aneurysms and improve diagnosis and …