Obesity and prostate cancer: weighing the evidence

EH Allott, EM Masko, SJ Freedland - European urology, 2013 - Elsevier
CONTEXT: Obesity and prostate cancer (PCa) affect substantial proportions of Western
society. Mounting evidence, both epidemiologic and mechanistic, for an association …

Caloric restriction

JR Speakman, SE Mitchell - Molecular aspects of medicine, 2011 - Elsevier
Restricting the intake of calories has been practiced as a method for increasing both the
length and quality of life for over 500years. Experimental work confirming the success of this …

The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women

M Harvie, C Wright, M Pegington… - British Journal of …, 2013 - cambridge.org
Intermittent energy restriction may result in greater improvements in insulin sensitivity and
weight control than daily energy restriction (DER). We tested two intermittent energy and …

[HTML][HTML] Cancer as a metabolic disease

TN Seyfried, LM Shelton - Nutrition & metabolism, 2010 - Springer
Emerging evidence indicates that impaired cellular energy metabolism is the defining
characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal …

Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients

C Lee, VD Longo - Oncogene, 2011 - nature.com
The dietary recommendation for cancer patients receiving chemotherapy, as described by
the American Cancer Society, is to increase calorie and protein intake. Yet, in simple …

[HTML][HTML] Roles of caloric restriction, ketogenic diet and intermittent fasting during initiation, progression and metastasis of cancer in animal models: a systematic review …

M Lv, X Zhu, H Wang, F Wang, W Guan - PloS one, 2014 - journals.plos.org
Background The role of dietary restriction regimens such as caloric restriction, ketogenic diet
and intermittent fasting in development of cancers has been detected via abundant …

Fasting and caloric restriction in cancer prevention and treatment

S Brandhorst, VD Longo - Metabolism in cancer, 2016 - Springer
Cancer is the second leading cause of death in the USA and among the leading major
diseases in the world. It is anticipated to continue to increase because of the growth of the …

Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients

EJ Fine, CJ Segal-Isaacson, RD Feinman, S Herszkopf… - Nutrition, 2012 - Elsevier
OBJECTIVE: Most aggressive cancers demonstrate a positive positron emission
tomographic (PET) result using 18F-2-fluoro-2-deoxyglucose (FDG), reflecting a glycolytic …

Insulin resistance and hyperinsulinaemia in the development and progression of cancer

IF Godsland - Clinical science, 2010 - portlandpress.com
Experimental, epidemiological and clinical evidence implicates insulin resistance and its
accompanying hyperinsulinaemia in the development of cancer, but the relative importance …

[HTML][HTML] The role of diet in cancer prevention and chemotherapy efficacy

SD Mittelman - Annual review of nutrition, 2020 - annualreviews.org
Despite great advances in treatment, cancer remains a leading cause of death worldwide.
Diet can greatly impact health, while caloric restriction and fasting have putative benefits for …