Bone-on-a-chip platforms and integrated biosensors: Towards advanced in vitro bone models with real-time biosensing

Y Zhang, T Yu, J Ding, Z Li - Biosensors and Bioelectronics, 2023 - Elsevier
Bone diseases, such as osteoporosis and bone defects, often lead to structural and
functional deformities of the patient's body. Understanding the complicated pathophysiology …

Review on bortezomib resistance in multiple myeloma and potential role of emerging technologies

G Kozalak, İ Bütün, E Toyran, A Koşar - Pharmaceuticals, 2023 - mdpi.com
Multiple myeloma is a hematological cancer type. For its treatment, Bortezomib has been
widely used. However, drug resistance to this effective chemotherapeutic has been …

Bone-on-a-chip: biomimetic models based on microfluidic technologies for biomedical applications

MK Kim, K Paek, SM Woo, JA Kim - ACS Biomaterials Science & …, 2023 - ACS Publications
With the increasing importance of preclinical evaluation of newly developed drugs or
treatments, in vitro organ or disease models are necessary. Although various organ-specific …

Mini-bones: miniaturized bone in vitro models

MG Fois, M van Griensven, S Giselbrecht… - Trends in …, 2024 - cell.com
In bone tissue engineering (TE) and regeneration, miniaturized,(sub) millimeter-sized bone
models have become a popular trend since they bring about physiological biomimicry …

The development, use, and challenges of electromechanical tissue stimulation systems

J Hu, W Anderson, E Hayes, EA Strauss… - Artificial …, 2024 - Wiley Online Library
Background Tissue stimulations greatly affect cell growth, phenotype, and function, and they
play an important role in modeling tissue physiology. With the goal of understanding the …

Energy Biomaterial Surface

D Nayak, A Behera - Surface Engineering of Biomaterials, 2024 - taylorfrancis.com
The current chapter describes an in-depth understanding of various surface properties of the
antibacterial nature of biomaterials and their adhesive properties with tissues. We focused …

The development, use, and challenges of electromechanical tissue stimulation systems

K Young-Bok Abraham, J Hu, W Anderson… - Authorea …, 2023 - essopenarchive.org
Tissues including lung, heart, and bone in the body are subjected to biological, electrical,
and mechanical stimulations. These stimulations greatly affect their growth, phenotype, and …

15 Energy Biomaterial

D Nayak, A Behera - Surface Engineering of Biomaterials …, 2024 - books.google.com
Transplant and repair of tissue have become an easy affair with continuous progress in cell
biology, medicine for tissue healing, and scaffolding of tissues, which facilitate the artificial …