The development of magnetic resonance imaging (MRI) for use in medical investigation has
provided a huge forward leap in the field of diagnosis, particularly with avoidance of …

The brain is unique among organs in many respects, including its mechanisms of lipid
synthesis and energy production. The nervous system-specific metabolite N-acetylaspartate …

Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …

Cell signaling via inositol phosphates, in particular via the second messenger myo‐inositol
1, 4, 5‐trisphosphate, and phosphoinositides comprises a huge field of biology. Of the nine …

The glutamatergic and dopaminergic systems are thought to be involved in the
pathophysiology of schizophrenia. Their interaction has been widely documented and may …

Background Recent developments in neuroimaging have advanced the understanding of
biological mechanisms underlying schizophrenia. However, neuroimaging correlates of …

Proton magnetic resonance spectroscopy (1H MRS) is a noninvasive imaging technique that
permits measurement of particular compounds or metabolites within the tissue of interest. In …

Myo‐inositol is an important part of the phosphatidylinositol second messenger system (PI‐
cycle). Abnormalities in nerve cell myo‐inositol levels and/or PI‐cycle regulation has been …

In vivo NMR spectroscopy is known as magnetic resonance spectroscopy (MRS). MRS has
been applied as both a research and a clinical tool in order to detect visible or nonvisible …

Background Proton magnetic resonance spectroscopy (1 H MRS) enables in-vivo
measurement of several relevant brain metabolites and has provided evidence of a range of …