Photoresponsive biomaterials for targeted drug delivery and 4D cell culture

ER Ruskowitz, CA DeForest - Nature Reviews Materials, 2018 - nature.com
Biological signalling is regulated through a complex and tightly choreographed interplay
between cells and their extracellular matrix. The spatiotemporal control of these interactions …

Bioelectronic medicine: preclinical insights and clinical advances

VA Pavlov, KJ Tracey - Neuron, 2022 - cell.com
The nervous system maintains homeostasis and health. Homeostatic disruptions underlying
the pathobiology of many diseases can be controlled by bioelectronic devices targeting CNS …

Optochemical control of biological processes in cells and animals

N Ankenbruck, T Courtney, Y Naro… - Angewandte Chemie …, 2018 - Wiley Online Library
Biological processes are naturally regulated with high spatial and temporal control, as is
perhaps most evident in metazoan embryogenesis. Chemical tools have been extensively …

Blue-light receptors for optogenetics

A Losi, KH Gardner, A Möglich - Chemical reviews, 2018 - ACS Publications
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Adverse effects of microplastics and nanoplastics on the reproductive system: A comprehensive review of fertility and potential harmful interactions

Y Hong, S Wu, G Wei - Science of The Total Environment, 2023 - Elsevier
In recent years, microplastics (MPs) and nanoplastics (NPs) have caused ubiquitous
environmental pollution and raised widespread concern about their potential toxicity to …

A red light–responsive photoswitch for deep tissue optogenetics

Y Kuwasaki, K Suzuki, G Yu, S Yamamoto… - Nature …, 2022 - nature.com
Red light penetrates deep into mammalian tissues and has low phototoxicity, but few
optogenetic tools that use red light have been developed. Here we present MagRed, a red …

Near‐infrared optogenetic genome engineering based on photon‐upconversion hydrogels

Y Sasaki, M Oshikawa, P Bharmoria… - Angewandte Chemie …, 2019 - Wiley Online Library
Photon upconversion (UC) from near‐infrared (NIR) light to visible light has enabled
optogenetic manipulations in deep tissues. However, materials for NIR optogenetics have …

CRISPR Cpf1 proteins: structure, function and implications for genome editing

F Safari, K Zare, M Negahdaripour… - Cell & bioscience, 2019 - Springer
CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive
immune system, allows biologists to edit genomic DNA in a precise and specific way …

Optogenetics for transcriptional programming and genetic engineering

TH Lan, L He, Y Huang, Y Zhou - Trends in Genetics, 2022 - cell.com
Optogenetics combines genetics and biophotonics to enable noninvasive control of
biological processes with high spatiotemporal precision. When engineered into protein …

Generating conditional gene knockouts in Plasmodium – a toolkit to produce stable DiCre recombinase-expressing parasite lines using CRISPR/Cas9

E Knuepfer, M Napiorkowska, C Van Ooij, AA Holder - Scientific reports, 2017 - nature.com
Successful establishment of CRISPR/Cas9 genome editing technology in Plasmodium spp.
has provided a powerful tool to transform Plasmodium falciparum into a genetically more …