In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles
H Arami, A Khandhar, D Liggitt… - Chemical Society …, 2015 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been extensively used during the last two decades,
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …
either as effective bio-imaging contrast agents or as carriers of biomolecules such as drugs …
In vivo biodistribution and clearance of magnetic iron oxide nanoparticles for medical applications
J Nowak-Jary, B Machnicka - International Journal of …, 2023 - Taylor & Francis
Magnetic iron oxide nanoparticles (magnetite and maghemite) are intensively studied due to
their broad potential applications in medical and biological sciences. Their unique …
their broad potential applications in medical and biological sciences. Their unique …
Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1
AC Illing, A Shawki, CL Cunningham… - Journal of Biological …, 2012 - ASBMB
Divalent metal-ion transporter-1 (DMT1) is a H+-coupled metal-ion transporter that plays
essential roles in iron homeostasis. DMT1 exhibits reactivity (based on evoked currents) with …
essential roles in iron homeostasis. DMT1 exhibits reactivity (based on evoked currents) with …
Cellular mechanisms of cadmium toxicity related to the homeostasis of essential metals
JM Moulis - Biometals, 2010 - Springer
The widespread occurrence of cadmium in the environment continues to pose a threat to
human health despite attempts at limiting its technological uses. The biologically significant …
human health despite attempts at limiting its technological uses. The biologically significant …
Manganese and the brain
K Tuschl, PB Mills, PT Clayton - International review of neurobiology, 2013 - Elsevier
Manganese (Mn) is an essential trace metal that is pivotal for normal cell function and
metabolism. Its homeostasis is tightly regulated; however, the mechanisms of Mn …
metabolism. Its homeostasis is tightly regulated; however, the mechanisms of Mn …
Physiologic implications of metal-ion transport by ZIP14 and ZIP8
S Jenkitkasemwong, CY Wang, B Mackenzie… - Biometals, 2012 - Springer
Zinc, iron, and manganese are essential trace elements that serve as catalytic or structural
components of larger molecules that are indispensable for life. The three metal ions possess …
components of larger molecules that are indispensable for life. The three metal ions possess …
Mechanisms of lead and manganese neurotoxicity
AP Neal, TR Guilarte - Toxicology research, 2013 - academic.oup.com
Human exposure to neurotoxic metals is a global public health problem. Metals which cause
neurological toxicity, such as lead (Pb) and manganese (Mn), are of particular concern due …
neurological toxicity, such as lead (Pb) and manganese (Mn), are of particular concern due …
Interactions of iron with manganese, zinc, chromium, and selenium as related to prophylaxis and treatment of iron deficiency
Iron (Fe) deficiency is considered as the most common nutritional deficiency. Iron deficiency
is usually associated with low Fe intake, blood loss, diseases, poor absorption …
is usually associated with low Fe intake, blood loss, diseases, poor absorption …
Manganese neurotoxicity: a focus on the neonate
KM Erikson, K Thompson, J Aschner… - Pharmacology & …, 2007 - Elsevier
Manganese (Mn) is an essential trace metal found in all tissues, and it is required for normal
amino acid, lipid, protein, and carbohydrate metabolism. While Mn deficiency is extremely …
amino acid, lipid, protein, and carbohydrate metabolism. While Mn deficiency is extremely …
Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells
H Fujishiro, Y Yano, Y Takada, M Tanihara… - Metallomics, 2012 - academic.oup.com
Chronic exposure to cadmium causes preferential accumulation of cadmium in the kidney,
leading to nephrotoxicity. In the process of renal cadmium accumulation, the cadmium …
leading to nephrotoxicity. In the process of renal cadmium accumulation, the cadmium …