[HTML][HTML] Guts imbalance imbalances the brain: a review of gut microbiota association with neurological and psychiatric disorders

L Mitrea, SA Nemeş, K Szabo, BE Teleky… - Frontiers in …, 2022 - frontiersin.org
In the last ten years, there has been a growing interest regarding the relationship between
gut microbiota, brain, and neurological-associated affections. As multiple preclinical and …

[HTML][HTML] HPA axis in the pathomechanism of depression and schizophrenia: new therapeutic strategies based on its participation

J Mikulska, G Juszczyk, M Gawrońska-Grzywacz… - Brain sciences, 2021 - mdpi.com
The hypothalamic-pituitary-adrenal (HPA) axis is involved in the pathophysiology of many
neuropsychiatric disorders. Increased HPA axis activity can be observed during chronic …

[HTML][HTML] Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review

RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …

Depression in neurodegenerative diseases: Common mechanisms and current treatment options

CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

[HTML][HTML] Understanding the role of interleukin-6 (IL-6) in the joint and beyond: a comprehensive review of IL-6 inhibition for the management of rheumatoid arthritis

EG Favalli - Rheumatology and therapy, 2020 - Springer
Rheumatoid arthritis (RA) is a chronic, debilitating autoimmune disorder involving
inflammation and progressive destruction of the joints, affecting up to 1% of the population …

[HTML][HTML] The immunopathogenesis of Alzheimer's disease is related to the composition of gut microbiota

F Leblhuber, D Ehrlich, K Steiner, S Geisler, D Fuchs… - Nutrients, 2021 - mdpi.com
The microbiota–gut–brain axis plays an important role in the development of
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …

[HTML][HTML] The relationship between stress and Alzheimer's disease

NJ Justice - Neurobiology of stress, 2018 - Elsevier
Stress is critically involved in the development and progression of disease. From the stress
of undergoing treatments to facing your own mortality, the physiological processes that …

Sex biology contributions to vulnerability to Alzheimer's disease: a think tank convened by the Women's Alzheimer's Research Initiative

HM Snyder, S Asthana, L Bain, R Brinton, S Craft… - Alzheimer's & …, 2016 - Elsevier
More than 5 million Americans are living with Alzheimer's disease (AD) today, and nearly
two-thirds of Americans with AD are women. This sex difference may be due to the higher …

[HTML][HTML] Neuroendocrine coordination of mitochondrial stress signaling and proteostasis

KM Berendzen, J Durieux, LW Shao, Y Tian, H Kim… - Cell, 2016 - cell.com
During neurodegenerative disease, the toxic accumulation of aggregates and misfolded
proteins is often accompanied with widespread changes in peripheral metabolism, even in …

[HTML][HTML] Pathogenetic and therapeutic applications of tumor necrosis factor-α (TNF-α) in major depressive disorder: a systematic review

K Ma, H Zhang, Z Baloch - International journal of molecular sciences, 2016 - mdpi.com
Major depressive disorder (MDD) is characterized by mood, vegetative, cognitive, and even
psychotic symptoms and signs that can cause substantial impairments in quality of life and …