[HTML][HTML] Interstitial lung disease in connective tissue disease: a common lesion with heterogeneous mechanisms and treatment considerations

T Shao, X Shi, S Yang, W Zhang, X Li, J Shu… - Frontiers in …, 2021 - frontiersin.org
Connective tissue disease (CTD) related interstitial lung disease (CTD-ILD) is one of the
leading causes of morbidity and mortality of CTD. Clinically, CTD-ILD is highly heterogenous …

[HTML][HTML] Myositis-related interstitial lung disease and antisynthetase syndrome

J Solomon, JJ Swigris, KK Brown - Jornal brasileiro de pneumologia, 2011 - SciELO Brasil
In patients with myositis, the lung is commonly involved, and the presence of anti-aminoacyl-
tRNA synthetase (anti-ARS) antibodies marks the presence or predicts the development of …

Hierarchical cluster and survival analyses of antisynthetase syndrome: phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity

B Hervier, H Devilliers, R Stanciu, A Meyer… - Autoimmunity …, 2012 - Elsevier
The clinical phenotype and evolution of antisynthetase syndrome (ASS) are heterogeneous.
This study was therefore undertaken to identify subgroups of ASS patients with similar …

Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease

H Andersson, M Sem, MB Lund, TM Aaløkken… - …, 2015 - academic.oup.com
Objective. To retrospectively evaluate the efficacy and safety of rituximab (Rtx) treatment in
patients with anti-synthetase syndrome (ASS) and severe interstitial lung disease (ILD) …

Clinical manifestations and treatment of antisynthetase syndrome

JL Marco, BF Collins - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
Antisynthetase syndrome (ASyS) is an autoimmune disease clinically manifested most often
by interstitial lung disease, myositis, and arthritis. Raynaud's syndrome, fever, and rashes …

Treatment of idiopathic inflammatory myositis associated interstitial lung disease: a systematic review and meta-analysis

T Barba, R Fort, V Cottin, S Provencher, I Durieu… - Autoimmunity …, 2019 - Elsevier
Objective Interstitial lung disease (ILD) is the most severe complication of idiopathic
inflammatory myositis (IIM), resulting in significant increase in morbidity and mortality and for …

Idiopathic inflammatory myopathies and the lung

JC Lega, Q Reynaud, A Belot, N Fabien… - European …, 2015 - Eur Respiratory Soc
Idiopathic inflammatory myositis (IIM) is a group of rare connective tissue diseases (CTDs)
characterised by muscular and extramuscular signs, in which lung involvement is a …

Clinical profiles and prognosis of patients with distinct antisynthetase autoantibodies

J Shi, S Li, H Yang, Y Zhang, Q Peng, X Lu… - The Journal of …, 2017 - jrheum.org
Objective. To compare the clinical characteristics and identify the longterm outcomes of
Chinese patients with different antisynthetase antibodies. Methods. We investigated …

Myositis-specific autoantibodies: their clinical and pathogenic significance in disease expression

H Gunawardena, ZE Betteridge, NJ McHugh - Rheumatology, 2009 - academic.oup.com
The idiopathic inflammatory myopathies (IIMs)—DM and PM—have been historically defined
by broad clinical and pathological criteria. These conditions affect both adults and children …

Overlap connective tissue disease syndromes

L Iaccarino, M Gatto, S Bettio, F Caso… - Autoimmunity …, 2013 - Elsevier
Overlap Syndromes (OSs) have been defined as entities satisfying classification criteria of at
least two connective tissue diseases (CTDs) occurring at the same or at different times in the …